Characterization of Cloned Mouse Na^+/taurocholate Cotransporting Polypeptide by Transient Expression in COS-7 Cells(Biochemistry & Molecular Biology)
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概要
- 論文の詳細を見る
The mouse Na^+/taurocholate cotransporting polypeptide transiently expressed in COS-7 cells caused sodium-dependent uptake of [^3H]taurocholic acid with K_m and V_<max> values of 18 μM and 102 pmol/mg protein/min, respectively. This K_m value is comparable to that for rat NTCP and higher than that for human NTCP. Substrate specificity was evaluated by measuring inhibitory effects of unlabeled bile acids on [^3H]taurocholic acid transport.
- 社団法人日本農芸化学会の論文
- 2002-05-23
著者
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Saeki Tohru
Laboratory of Molecular Nutrition, Kyoto Prefectural University
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IWAMI Kimikazu
Laboratory of Molecular Nutrition, Kyoto Prefectural University
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KANAMOTO Ryuhei
Laboratory of Molecular Nutrition, Kyoto Prefectural University
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Iwami K
Lab. Of Molecular Nutrition Kyoto Prefectural Univ.
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Saeki Tohru
Laboratory Of Molecular Nutrition Department Of Biological Resource Chemistry Kyoto Prefectural Univ
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Iwami Kimikazu
Laboratory Of Food And Nutritional Sciences Department Of Agricultural Chemistry Kyoto Prefectural U
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Kanamoto R
Lab. Of Molecular Nutrition Kyoto Prefectural Univ.
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Kanamoto Ryuhei
Laboratory Of Molecular Nutrition Department Of Biological Resource Chemistry Kyoto Prefectural Univ
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Saeki Tohru
Laboratory Of Molecular Nutrition Kyoto Prefectural University
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TAKAHASHI Noriki
Laboratory of Vital & Molecular Nutrition, Department of Biological Resource Chemistry, Faculty of A
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Takahashi Noriki
Laboratory Of Vital & Molecular Nutrition Department Of Biological Resource Chemistry Faculty Of
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KANAMOTO Ryuhei
Laboratory of Food and Nutrition Department of Agricultural Chemistry, Kyoto Prefectural University
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