A Novel Membrane Protein Complex on the Endoplasmic Reticulum and Early Golgi Compartments in the Yeast Saccharomyces cerevisiae(Biochemistry & Molecular Biology)

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概要

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• A novel membrane protein, Yml067c in the systematic ORF name, was discovered as a component of immunoisolated vesicles of the early Golgi compartment of the yeast Saccharomyces cerevisiae (Cho et al., FEBS Lett. 469,151-154 (2000)). Conserved sequences having sequence similarity to Yml067c were widely distributed in the eukaryotes and one of them, Yal042w, was found in the Saccharomyces genome database. In the yeast cell, Yml067c and Yal042w were found to form a heterooligomeric complex by immunoprecipitation of their tagged derivatives from the detergent-solubilized membrane. Cell fractionation and indirect immunofluorescent staining indicated that the majority of these proteins were localized on the ER membrane. Therefore, the Yml067c-Yal042w complex should shuttle between the ER and the early Golgi compartment as well as the p24-family proteins.

• 社団法人日本農芸化学会の論文
• 2001-10-23

著者

• YODA Koji

  Department of Biotechnology, University of Tokyo

• Adachi Hideya

  Department Of Biofunctional Chemistry Faculty Of Agriculture Kobe University

• Yoda K

  Univ. Tokyo Tokyo Jpn

• Yoda Koji

  Department Of Biotechnology University Of Tokyo

• NODA Yoichi

  Department of Biotechnology, University of Tokyo

• ADACHI Hiroyuki

  Department of Biotechnology, University of Tokyo

• CHO Jung-Hwa

  Department of Biotechnology, the University of Tokyo

• Cho Jung-hwa

  Department Of Biotechnology The University Of Tokyo

• Yamane K

  Univ. Tsukuba

• Noda Y

  Univ. Tokyo Tokyo Jpn

• Noda Y

  Department Of Gynecology And Obstetrics Kyoto University Faculty Of Medicine

• Yoda Koji

  Department Of Agricultural Chemistry The University Of Tokyo

• Adachi Hiroyuki

  Department Of Biotechnology Graduate School Of Agricultural And Life Sciences University Of Tokyo

• Noda Yoichi

  Department Of Biotechnology University Of Tokyo

• Yoda K

  Institute Of Biological Sciences University Of Tsukuba

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