Milk Basic Protein Promotes Bone Formation and Suppresses Bone Resorption in Healthy Adult Men

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概要

• 論文の詳細を見る

• Milk contains several components effective for bone health. In the previous in vitro and in vivo studies, we have shown that milk whey protein, especially its basic protein fraction (milk basic protein [MBP]), promoted bone formation and suppressed bone resorption. This present study examines the effect of MBP on the biochemical markers of bone metabolism in healthy adult men. Experimental beverages containing MBP (300 mg of MBP a day) were given to 30 normal healthy adult men for 16 days. The serum osteocalcin concentration had increased significantly after 16 days of ingesting the experimental beverage containing MBP. Urinary cross-linked N-teleopeptides of type-I collagen (NTx) excretion had decreased significantly after 16 days of ingesting MBP. The urinary NTx excretion was related to the serum osteocalcin concentration after 16 days of ingestion. These results suggest that MBP promoted bone formation and suppressed bone resorption, while maintaining the balance of bone remodeling.

• 社団法人日本農芸化学会の論文
• 2001-06-23

著者

• Toba Y

  Snow Brand Milk Products Co. Ltd. Saitama Jpn

• Aoki T

  Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University

• Toba Yasuhiro

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Takada Yukihiro

  雪印乳業技術研究所

• MORITA Yoshikazu

  Technology and Research Institute, Snow Brand Milk Products Co., Ltd.

• TAKADA Yukihiro

  Technology and Research Institute, Snow Brand Milk Products Co., Ltd.

• KAWAKAMI Hiroshi

  Technology and Research Institute, Snow Brand Milk Products Co., Ltd.

• MATSUOKA Yasuhiro

  Technology and Research Institute, Snow Brand Milk Products Co. Ltd.

• KUMEGAWA Masayoshi

  Department of Oral Anatomy, Meikai University School of Dentistry

• AOE Seiichiro

  Technology and Research Institute, Snow Brand Milk Products Co., Ltd.

• AOE Seiichiro

  Product Planning Department, Snow Brand Milk Products Co., Ltd.

• MOTOURI Mutsumi

  Technology and Research Institute, Snow Brand Milk Products Co. Ltd.

• ITABASHI Akira

  Central Clinical Laboratory, Saitama Medical School

• HIRAI Tomoko

  Product Planning Department, Snow Brand Milk Products Co. Ltd.

• SUGURI Toshiaki

  Product Planning Department, Snow Brand Milk Products Co. Ltd.

• TAKEUCHI Akira

  Luke Hospital

• Aoe Seicihiro

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Morita Y

  Japan Advanced Inst. Of Sci. And Technol. School Of Materials Sci. Ishikawa

• Morita Y

  Kyoto Univ. Kyoto‐shi

• Takada Y

  Snow Brand Milk Products Co. Ltd. Saitama Jpn

• Toba Y

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Takada Y

  Hokkaido Univ. Hokkaido Jpn

• Takada Yasuhiro

  Hokkaido Univ. Sapporo Jpn

• Hirai Tomoko

  Product Planning Department Snow Brand Milk Products Co. Ltd.

• Aoe Seiichiro

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Takeuchi Yoji

  Cell Function And Structure Division Of Biological Sciences Graduate School Of Science Hokkaido Univ

• Morita Y

  Central Research Institute Tsukuba R&d Center Fuji Oil Co. Ltd.

• Suguri Toshiaki

  Product Planning Department Snow Brand Milk Products Co. Ltd.

• Suguri Toshiaki

  Technical Research Institute Snow Brand Milk Products Co. Ltd.

• Motouri Mutsumi

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Motouri Mutsumi

  Technology And Research Instittue Snow Brand Milk Products Co. Ltd.

• Yahiro Masatoshi

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Morita Yoshikazu

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Kumegawa Masayoshi

  Department Of Oral Anatomy Josai Dental University

• Aoe Seiichiro

  Product Planning Department Snow Brand Milk Products Co. Ltd.

• Takeda Yuichi

  Fac. Sci. And Tech. Keio Univ. Yokohama

• Itabashi Akira

  Central Clinical Laboratory Saitama Medical School

• Takeuchi A

  Department Of Biological Science Faculty Of Science Nara Women's University

• Kawakami H

  Technology And Research Institute Snow Brand Milk Products Co. Ltd.

• Kawakami Hiroshi

  Technical Research Institute Snow Brand Milk Products Co. Ltd.

• 竹内 章

  Tohoku Univ. Sendai Jpn

• TAKADA Yukihiro

  Technology and Research Institute, and Nutritional Science Laboratory

• TAKADA Yukihiro

  Technology & Research Institute, Snow Brand Milk Products Co., Ltd.

• TOBA Yasuhiro

  Technology & Research Institute, Snow Brand Milk Products Co., Ltd.

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