Natural Antioxidant, Chlorogenic Acid, Protects Against DNA Breakage Caused by Monochloramine
スポンサーリンク
概要
- 論文の詳細を見る
Chlorogenic acid prevented a stepwise conversion of plasmid pUC18 DNA, form I→form II→form III, induced by 3 mM monochloramine with a half inhibition of 67.4 μM. Chlorogenic acid reacted with monochloramine in a timedependent manner, and the reaction rate increased with decreasing pH. These results suggest that chlorogenic acid prevents genotoxicity of monochloramine in gastric mucosa.
- 社団法人日本農芸化学会の論文
- 1999-07-23
著者
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SAKAMOTO Yuji
Department of Aerospace Engineering, Tohoku University
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KONO Yasuhisa
Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane Uni
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SHIBATA Hitoshi
Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane Uni
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Kono Yasuhisa
Department Of Life Science And Biotechnology Faculty Of Life And Environmental Science Shimane Unive
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Kono Yasuhisa
Department Of Bacteriology Faculty Of Medicine Tottori University
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Shibata Hiroyuki
Institute For Chemical Research Kyoto University
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OKA Mikiko
Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane Uni
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Oka Mikiko
Department Of Life Science And Biotechnology Faculty Of Life And Environmental Science Shimane Unive
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Sakamoto Y
Nihon Univ. Kanagawa Jpn
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Sakamoto Yuji
Department Of Aeronautics And Astronautics
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Shibata H
Dept. Life Environ. Sci. Shimane Univ.
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Sawa Yoshihiro
Dept. Life Environ. Sci. Shimane Univ.
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Kono Y
Department Of Life Science And Biotechnology Faculty Of Life And Environmental Science Shimane Unive
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Sawa Yoshihiro
Dept. Appl. Biosci. And Biotech. Fac. Life And Environ. Sci. Shimane Univ.
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Sakamoto Yoko
Department Of Food Science And Technology College Of Bioresouce Sciences Nihon University
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Oka Mikio
Department Of Respiratory Medicine Kawasaki Medical School
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Shibata Hitoshi
Department Of Applied Biological Science Faculty Of Agriculture Shimane University
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SHIBATA Hitoshi
Department of Agricultural Chemistry, Faculty of Agriculture, Shinshu University
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Oka Mikio
Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
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