Action of FR901228, a Novel Antitumor Bicyclic Depsipeptide Produced by Chromobacterium violaceum No. 968, on Ha-ras Transformed NIH3T3 Cells
スポンサーリンク
概要
- 論文の詳細を見る
FR901228, a novel antitumor antibiotic, reversed the transformed morphology of the Ha-ras transformants, Ras-1 cells, and inhibited their growth. The reduction of c-myc expression was observed in FR901228-treated Ras-1 cells by RNA dot-blot hybridization. This reduction of c-myc expression and morphological reversion of the transformed cells to normal were correlated with growth inhibition (G_0/G_1 arrest in cell cycle).
- 社団法人日本農芸化学会の論文
- 1994-09-23
著者
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Nakajima Hiroo
京都府立医科大学 内分泌・乳腺外科学部門
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Nakajima Hiroo
Tsujigiwa Daigo Clinic 1-19 Daigo Shinmachi-uramachi Fushimi-ku Kyoto 601-1326 Jpn
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OKUHARA Masakuni
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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UEDA HIROTSUGU
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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HORI Yasuhiro
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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Nakajima H
Department Of Endocrine Breast Surgery Kyoto Prefectural University Of Medicine
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NAKAJIMA Hidenori
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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Goto Toshio
,Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
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Hori Yasuhiro
Fermentation Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Hori Y
Division Of Bioscience And Biotechnology Department Of Ecological Engineering Toyohashi University O
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Hori Yasuhiro
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Ueda Horotsugu
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Ueda Hirotsugu
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Ueda H
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Okuhara M
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Okuhara Masakuni
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Nakajima Hidenori
Exploratory Research Laboratories Fujisawa Pharmaceutical Co. Ltd
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