SKIN SENSITIZATION AND PHOTOSENSITIZATION STUDIES OF HYDROPHOBICALLY MODIFIED HYDROXYPRORYL METHYLCELLULOSE IN GUINEA PIGS
スポンサーリンク
概要
- 論文の詳細を見る
Skin sensitization and photosensituzation tests of hydrophobically modified hydroxypropyl methylcellulose(HM-HPMC), a new cellulose derivative used as a thickener for topical pharmaceuticals, were conducted using guinea pigs. An aqueous dispersion of HM-HPMC(3 w/v %)was applied in the tests. Skin reaction was not observed in any animal in the HM-HPMC-treated group or control group. In the photosensitization test, no skin reaction was found in any animal in the test-preparation group or the control group. It was concluded that the HM-HPMC dispersion does not exhibit skin sensitizing or photosensitizing activity under the condition of this test.
- 日本トキシコロジー学会の論文
- 1998-07-28
著者
-
田中 修
甲南大・理工・生物
-
Tanaka O
Institute Of Pharmaceutical Sciences Faculty Of Medicine Hiroshima University
-
鎌田 喜一郎
長岡技術科学大学化学系
-
Tanaka O
Department Of Biology Faculty Of Science And Engineering Konan University
-
Tanaka O
Shimane Medical University
-
Obara S
Shin‐etsu Chemical Co. Ltd. Niigata Jpn
-
Obara Sakae
Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
-
Otsuka Michio
Bio-medical Research Laboratories Co. Ltd.
-
MARUYAMA Kazumasa
Specialty Chemicals Research Center, Shin-Etsu Chemical Co., Ltd.
-
ICHIKAWA Naoto
Bio-Medical Research Laboratories Co., Ltd.
-
TANAKA Osamu
Bio-Medical Research Laboratories Co., Ltd.
-
OHTSUKA Michio
Bio-Medical Research Laboratories Co., Ltd.
-
KAWANABE Mikiko
Bio-Medical Research Laboratories Co., Ltd.
-
NIIKURA Yoshiyuki
Bio-Medical Research Laboratories Co., Ltd.
-
TENNICHI Makoto
Bio-Medical Research Laboratories Co., Ltd.
-
SUZUKI Akio
Mitsubishi-Kasei Institute of Toxicological and Environmental Sciences
-
HOSHINO Nobuto
Mitsubishi-Kasei Institute of Toxicological and Environmental Sciences
-
OHWADA Kyoko
Mitsubishi-Kasei Institute of Toxicological and Environmental Sciences
-
Tennichi Makoto
Bio-medical Research Laboratories Co. Ltd.
-
Ichikawa Naoto
Bio-medical Research Laboratories Co. Ltd.
-
Tanaka O
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
-
Maruyama Kazumasa
Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
-
Niikura Yoshiyuki
Bio-medical Research Laboratories Co. Ltd.
-
Suzuki A
Mitsubishi-kasei Institute Of Toxicological And Environmental Sciences
-
Kawanabe Mikiko
Bio-medical Research Laboratories Co. Ltd.
関連論文
- 37.エピネフリン誘導体の花芽分化誘導活性(口頭発表,植物化学調節学会第41回大会)
- 高周波スパッタリングによるMgO薄膜の配向性と微細構造(セラミックスの微細構造)
- Identification of reaction products of 9-hydroxy-10-oxo-12(Z), 15(Z)-octadecadienoic acid (KODA) and norepinephrine that strongly induce flowering in Lemna
- HIPを利用した高密度ペロブスカイトLaNiO_3の作製
- プラズマCVD法による硬質アモルファス窒化ホウ素膜の作製
- 55.アオウキクサ151系統のストレスによる花芽誘導因子の生産(第36回大会研究発表抄録)
- 55 アオウキクサ151系統のストレスによる花成誘導因子の生産
- ホウ酸アルミニウムウィスカーによるイネカルスへの遺伝子導入
- アセチルアセトンによるZn0膜のエッチング
- プラズマCVD法によるSiN_xC_y膜の熱的安定性
- 反応性スパッタリングによるSiC_x膜の機械的性質
- プラズマCVD-SiNxCy膜のEPMAによる組成分析
- HIPによる金属表面上へのセラミックスコーティング
- 718 HIP による金属表面上へのセラミックスコーティング(セラミックス : 焼結, 破壊特性, 被覆, 萌芽・境界技術, 日本鉄鋼協会第 114 回(秋季)講演大会)
- 70 アズキ (丹波大納言) の植物体再生と遺伝子導入
- Sweet Cucurbitane Glycosides from Fruits of Siraitia siamensis (chi-zi luo-han-guo), a Chinese Folk Medicine(Organic Chemistry)
- PC76 SOLUBILIZATION OF SAIKOSAPONIN-a AND α-TOCOPHEROL WITH PLANT GLYCOSIDES
- RETICULOENDOTHELIAL SYSTEM ACTIVATING POLYSACCHARIDES FROM Panax SPP : P. notoginseng, P. ginseng and P. japonicus
- Saponins of Plants of Panax Species Collected in Central Nepal, and Their Chemotaxonomical Significance. III.
- Bioactive Saponins and Glycosides. XI. Structures of New Dammarane-Type Triterpene Oligoglycosides, Quinquenosides I, II, III, IV, and V, from American Ginseng, the Roots of Panax quinquefolium L.
- Bioactive Saponins and Glycosides. IX. Notoginseng (2) : Structures of Five New Dammarane-Type Triterpene Oligoglycosides, Notoginsenosides-E, -G, -H, -I, and -J, and a Novel Acetylenic Fatty Acid Glycoside, Notoginsenic Acid β-Sophoroside, from the Dried
- Bioactive Saponins and Glycosides. VIII. Notoginseng (1) : New Dammarane-Type Triterpene Oligoglycosides, Notoginsenosides-A, -B, -C, and -D, from the Dried Root of Panax notoginseng (BURK.) F. H. CHEN
- TiN-TiB_2系常圧焼結体の機械的及び電気的特性
- プラズマ CVD 法による Si_3N_4-SiC 系薄膜の直流電気伝導特性
- 各種焼結助剤添加ホットプレスTiNセラミックスの機械的特性
- ECRプラズマCVD法による硬質炭素膜の合成 (超薄膜--その機能と制御)
- ECR型プラズマCVD法により合成された炭素薄膜の表面組織とプラズマ発光スペクトル強度
- ホットプレス法による窒化チタンセラミックスの強度及び電気的特性
- ホットプレス法によるTiNセラミックスの特性--焼結助剤添加の影響
- 高周波プラズマCVD法による炭素膜へのバイアス効果
- アセチルアセトンによるMgO薄膜のエッチング
- Effects of Spaceflight on Enzyme Activities and Ultrastructure of Fast-Type Skeletal Muscles of Rats
- A-band Movement and Junctional Gap Dissociation during Caffeine-induced Contracture of Skeletal Muscle Fibers
- Study on Improvement of Sweetness of Steviol Bisglycosides: Selective Enzymic Transglucosylation of the 13-O-Glycosyl Moiety
- アミスギギタケの暗黒下での子実体原基形成
- Substrate Specificity of Glycyrrhizinic Acid Hydrolase(Organic Chemistry)
- 143 アズキ (丹波大納言小豆) の毛状根の誘導と不定芽の分化
- ナンゴクアアオウキクサ(Lemna aequinoctialis)の染色体倍数系列の存在
- 2Ba-10 大気湿度が水稲葉の生長と老化に及ぼす影響
- ネナシカズラ(Cuscuta japonica)の日長感受部
- Morphological analysis of neural tube defects : Chlorambucil-induced exencephaly in mice
- Identification and Quantification of 20(S)-Protopanaxatriol and its 20S, 24S-Epoxide in Human Urine with the Treatment of A1kaline Cleavage after the Ingestion of Sanchi Ginseng, the Roots of Panax notoginseng(三七人参)
- Antimicrobial Activities of Saponins of Pericarps of Sapindus mukurossi on Dermatophytes
- Inhibition of Aldose Reductase and Sorbitol Accumulation by Astilbin and Taxifolin Dihydroflavonols in Engelhardtia chrysolepis
- Studies of the Constituents of Astragalus membranaceus BUNGE. III. Structure of Triterpenoidal Glycosides, Huangqiyenins A and B, from the Leaves
- Protection against Oxidative Damage by Dihydroflavonols in Engelhardtia chrysolepis
- Sweetness of Glycyrrhetic Acid 3-O-β-D-Monoglucuronide and the Related Glycosides
- Enzymic Production of Sweet Stevioside Derivatives : Transglucosylation by Glucosidases(Organic Chemistry)
- Further Study on the 1,4-α-Transglucosylation of Rubusoside, a Sweet Steviol-Bisglucoside from Rubus suavissimus(Organic Chemistry)
- Production of Stevioside and Rubusoside Derivatives by Transfructosylation of β-Fructofuranosidase(Biological Chemistry)
- Chemical Studies on Fuku-bon-shi : a Dimer of Glucosyl Esters of 19α-Hydroxyursolic Acid Derivatives from Rubus coreanus and its Significance for Identification of the Source Plants
- Production of Rubusoside Derivatives by Transgalactosylation of Various α-Galactosidases(Biological Chemistry)
- Production of Rubusoside Derivatives by Transgalactosylation of Various β-Galactosidases(Biological Chemistry)
- Enzymic Transglucosylation Products of Stevioside: Separation and Sweetness-evaluation(Food & Nutrition)
- BIOLOGICALLY ACTIVE POLYSACCHARIDE FROM SANCHIGINSENG, ROOTS OF PANAX NOTOGINSENG
- Rubusoside (β-D-Glucosyl Ester of 13-O-β-D-Glucosyl-steviol), a Sweet Principle of Rubus chingii Hu (Rosaceae)
- 66 大気湿度を異にした場合における吸水阻害が水稲の生長, 乾物生産に及ぼす影響
- レーザーCVDによるTiO_2膜の合成
- Isolation of Protoplast from Aerial Mycelia and Fruit-Body Formation from Regenerated Mycelia in Pleurotus cornucopiae
- Improvement of the Aluminum Borate Whisker-Mediated Method of DNA Delivery into Rice Callus(Cell and Molecular Biology)
- Plant regeneration in Actinidia polygama Miq. by leaf, stem, and petiole culture with zeatin, and from stem-derived calli on low-sucrose medium
- Varietal Differences in the Morphophysiological Response to Atmospheric Humidity in Rice
- Studies on the Effect of the Relative Humidity of the Atmosphere on the Growth and Physiology of Rice Plants : Effects of relative humidity during the light and dark periods on the growth
- Aluminium Borate Whisker-Mediated DNA Delivery into Callus of Rice and Production of Transgenic Rice Plant
- Inhibition of Flower Induction by Some Inhibitors of Protease in the Short-day Plant Lemna paucicostata 6746 and the Long-day Plant Lemna gibba G3
- Comparison between Induction of Flowering by Nitrogen Deficiency and that by Short Days or Continuous Irradiation with Blue or Low-Intensity White Light in Lemna paucicostata 6746
- プラズマCVD法によるSi_3N_4-SiC系非晶質膜の軽イオンビーム照射損傷
- Effects of Exogenous Amino Acids on Iron Uptake in Relation to their Effects on Photoperiodic Flowering in Lemna paucicostata 6746
- Measurement of Endogenous Phosphorus Levels in Relation to Flowering in the Long-Day Plant Lemna gibba G3
- プラズマCVD法によるSi_3N_4-SiC系セラミックス薄膜の合成
- Flower Induction by Suppression of Nitrate Assimilation in Lemna paucicostata 6746
- PHOTOPERIODIC FLOWERING OF CUSCUTAJAPONICA
- Photoperiodic Flowering of Cuscuta japonica Cultured In Vitro
- Identification of a Component that Induces Flowering of Lemna among the Reaction Products of α-Ketol Linolenic Acid (FIF) and Norepinephrine
- CHEMICAL STRUCTURE OF THE MAJOR COMPONENTS OF REACTANTS BETWEEN FIF AND NOREPINEPHRINE WHICH STRONGLY INDUCE FLOWER FORMATION OF LEMNA
- Morphological Changes of Unmyelinated Nerves in the Cerebral Arteries after Removal of the Pterygopalatine Ganglion : An Electron Microscopic Study
- Morphological Analysis of Neural Tube Defects in Non-obese Diabetic (NOD) Mouse Embryos
- Flowering Induced by Nitrogen Deficiency in Lemna paucicostata 151
- プロトプラストの迅速単離法
- サツキツツジ(Rhododendron indium)の開花反応
- 2Ea01 窒素代謝抑制によるアオウキクサの花芽分化誘導
- 3Ca-6 短日性アオウキクサLemna paucicostata 6746の硝酸還元抑制による花芽分化誘導
- Transgenic Plant Regeneration Through Silicon Carbide Whisker-Mediated Transformation of Rice (Oryza sativa L.)
- SKIN SENSITIZATION AND PHOTOSENSITIZATION STUDIES OF HYDROPHOBICALLY MODIFIED HYDROXYPRORYL METHYLCELLULOSE IN GUINEA PIGS
- A REPEATED-DOSE DERMAL TOXICITY STUDY OF HYDROPHOBICALLY MODIFIED HYDROXYPROPYL METHYLCELLULOSE IN RATS
- Innervation of human developing extraocular muscles : immunohistochemical study
- PRIMARY DERMAL AND EYE IRRITABILITY TESTS OF HYDROPHOBICALLY MODIFIED HYDROXYPROPYL METHYLCELLULOSE IN RABBITS
- STUDIES ON SINGLE-DOSE TOXICITY OF HYDROPHOBICALLY MODIFIED HYDROXYPROPYL METHYLCELLULOSE IN RATS
- Flower-Inducing Activity of Lysine in Lemna paucicostata 6746
- Flower-Inducing Activity of Exogenous Lysine in Lemna paucicostata 151 Cultured on Nitrogen-Rich Medium : GROWTH AND DEVELOPMENT
- Lysine Reverses the Inhibition of Flowering by Elastatinal, a Protease Inhibitor, in Lemna paucicostata 151
- Flower-Inducing Activity of Lysine in Lemna paucicostata 151 Cultured on Nitrogen-Deficient Medium : GROWTH AND DEVELOPMENT : PROTEINS, ENZYMES AND METABOLISM
- In vivo analysis of RGD-sequence dependent cortical histogenesis in mouse telencephalon
- Effects of Chlorambucil on the Brain Development in Mice during Post-neurulation Period
- プラズマCVD法によるアモルファス炭・窒化物膜
- 低温プラズマCVDによる炭・窒化物膜の合成 (セラミックスへのプラズマ利用)
- CYTOCHEMISTRY OF CA^-ATPASE ACTIVITY IN THE RAT SPINAL CORD DURING EMBRYONIC DEVELOPMENT
- Identification and Quantification of 20(S)-Protopanaxatriol and its 20S, 24S-Epoxide in Human Urine with the Treatment of A1kaline Cleavage after the Ingestion of Sanchi Ginseng, the Roots of Panax notoginseng(三七人参)
- Antimicrobial Activities of Saponins of Pericarps of Sapindus mukurossi on Dermatophytes
- 軽イオンビ-ム照射したステンレス鋼のEPMAによる組成分析