EFFECT OF MITOMYCIN C ON BONE MARROW CELLS IN MICE
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概要
- 論文の詳細を見る
The total and differential Cell counts of femoral bone marrow and peripheral reticulocyte counts were determined in male ddY mice up to day 11 after an intraperitoneal injection of 2 mg/kg of mitomycin C. 1. Total marrow cell counts showed a minimum value on day 2 after the injection, and then recovered to the control level on day 7. 2. In the differential cell counts, the minimum values were observed on day 1 for proerythroblasts and basophilic erythroblasts, on day 2 for polychromatic erythroblasts, and on day 4 for mature neutrophils. Recovery was seen from the 4th to 7th days after injection. Marrow lymphocytes showed a maximum value when the total counts were minimum. 3. The peripheral reticulocytes almost disappeared 4 days after the injection, and recovered to the pretreatment level on day 11.
- 日本トキシコロジー学会の論文
- 1984-02-25
著者
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Furuya Tsuyoshi
Division of Toxicology, National Institute of Health Sciences
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MATSUMOTO Kiyoshi
Division of Toxicology, National Institute of Hygienic Sciences
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TOBE Masuo
Division of Toxicology, National Institute of Hygienic Sciences
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FURUYA Tsuyoshi
Biological Safety Research Center, National Institute of Health Science
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TOBE Masuo
Natl. Inst. Hyg. Sci.
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Matsumoto K
Drug Safety Research Laboratories Pharmaceutical Research Division Takeda Chemical Industries Ltd.:l
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Tobe Masuo
Division Of Toxicology National Institute Of Hygienic Sciences
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Tobe M
Laboratory Of Signal Transduction Institute For Molecular And Cellular Regulation Gunma University
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Tobe Masuo
Division Of Toxicology Biological Safety Research Center National Institute Of Hygienic Sciences
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Furuya Tsuyoshi
Biological Safety Research Center National Institute Of Health Science
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Matsumoto Kiyoshi
Division Of Food Biotechnology Department Of Bioscience And Biotechnology Faculty Of Agriculture Gra
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Matsumoto Kiyoshi
Division of Bioscience and Bioenvironmental Sciences, Faculty of Agriculture, Graduate School of Kyushu University
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