胃潰瘍と十二指腸潰瘍の心身医学的側面における比較研究

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In order to clarify the differences in psychic and neural aspects between gastric ulcer and duodenal ulcer, studies were carried out in which matched pair controls were employed, and the following results were obtained : 1) The MPI patterns in patients with gastric ulcer were similar to those in the controls ; on the other hand, the MPI patterns in patients with duodenal ulcer charaterized with a remarkable neurotic tendency. 2) Basal respiratory arrythmia was more remarkable in ulcer cases than in the controls, being more remarkable in cases with gastric ulcer than in cases with duodenal ulcer. A similar tendency was also observed in the reductions of pulse rate in response to Aschner's test. 3) The observation of mecholyl response types revealed a reduction of N-type responses with an increase of P-type responses in cases with gastric ulcer, while in cases with duodenal ulcer, an even more increased incidence of abnormal response types was noted, with a further reduction of N-type responses and an increase of S-type responses. 4) Observations of gastric secretory functions revealed that the acid secretory responses to insulininduced hypoglycemia and to gastrin injection were greater in cases with duodenal ulcer than in cases with gastric ulcer. 5) Experimental studies in rats revealed that the secretory stimulation with insulin resulted in a significantly increased incidence of gastric ulcer induced by a restraint under cold atmosphere, although no ulcer formation was observable in the duodenum, regardless of the methods used for the stimulation of gastric secretion.
日本心身医学会の論文

胃潰瘍と十二指腸潰瘍の心身医学的側面における比較研究

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