胃潰瘍の総合医学的治療研究(1) : Placebo投与入院安静療法を中心とする結果について

概要

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In connection with a series of studies on the comprehensive medical treatment of peptic ulcers, this first report deals with a clinical study of the inpatient treatment with placebo and also of the factors influencing the rate of healing of gastric ulcers. A total of 60 in-patients, each of whom had an active single round ulcer, were given placebo. The healing rate for the 60 patients was 23.3% (14) at the end of the 4th week, 63.8% (41) at the end of the 8th week, and 24 out of 27 patients (88.9%) were healed within 12 weeks. Some factors influencing the time required for ulcer healing were analyzed; there was a significant correlation (P<0.02) between the age of patients and the size of ulcer niche and the healing time. The results suggested that the basic factors influencing the natural healing of gastric ulcers were 1) physical and mental rest, 2) age of patient and size of ulcer niche. Accordingly, the time required for ulcer healing might be estimated by taking into due consideration of the age of patient and the size of ulcer in treating gastric ulcer. The prospect for treatment of gastric ulcer was also discussed.
日本心身医学会の論文
1977-10-01