<研究資料>病気の顔貌と容貌(1) : 先端肥大症(Acromegaly)について

概要

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Acromegaly is the clinical condition which results from prolonged, excessive circulating levels of growth hormone (GH) in adults, which occurs in the young before epiphyseal fusion, is called pituitary giantism. Acromegaly was first described in 1886 by Pierre Marie, who noted “a striking non-congenital hypertrophy of the extremities". Benign pituitary tumors are by far the most common cause of acromegaly. Whether the tumor results from a hypothalamic disturbance or a primary pituitary tumor is unknown at present. Acromegaly is a desease of the whole organism where everything but the central nervous system enlarges. Although the diagnosis is often made accidentally, the patient usually presents complaining of a change in appearance of the face, hands or whole body, headaches, sweating, goiter or secondary symptoms of pituitary enlargement. In this report, we presented typical cases with acromegaly. Early diagnosis is important but this depends upon a high index of suspicion. It often helps to look at old photographs as shown by ours.
九州大学の論文
1990-03-28