ブタおよびウシ卵胞退行中の顆粒層および内卵胞膜細胞におけるアポトーシス細胞局在の種差について
スポンサーリンク
概要
- 論文の詳細を見る
Species-specific differences in the process of apoptosis in granulosa and theca layers during follicular atresia in porcine and bovine ovaries were investigated by in situ DNA 3’end-labeling (TUNEL) at the level of individual cells. In porcine ovaries, granulosa cells located on the inner surface of the granulosa layer appeared to undergo apoptosis at the first stage, followed by neighboring granulosa cells. In the contrast, granulosa cells located on the middle region appeared to undergo apoptosis at the first stage in bovine ovaries. In both porcine and bovine ovaries, detachment and degeneration of the granulosa cell layer and fragmentation of basement membrane occurred in the follicles at advanced stage of atresia. In the ovaries of both species, theca interna cells were still intact at the stage of early atresia and then apoptotic cells appeared in the late to final stages of atresia, but no apoptotic cells were observed in theca externa layers during follicular atresia. The present findings indicated that apoptosis occurring in granulosa cells is an initial symptom of follicular atresia in the ovaries of both species, and that the apoptosis inducing factor(s) and/or survival factor(s) for the granulosa cells may be different between porcine and bovine ovaries.
- 日本繁殖生物学会の論文
- 2000-06-01
著者
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Nishimura Shotaro
Kyushu Univ. Fukuoka Jpn
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眞鍋 昇
Unit of Anatomy and Cell Biology, Department of Animal Sciences, Kyoto University
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MIYAMOTO Hajime
Unit of Anatomy and Cell Biology, Department of Animal Sciences, Kyoto University
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NAKAYAMA Mizuho
Unit of Anatomy and Cell Biology, Department of Animal Sciences, Kyoto University
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中山 瑞穂
Unit of Anatomy and Cell Biology, Department of Animal Sciences, Kyoto University
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西原 晋
Unit of Anatomy and Cell Biology, Department of Animal Sciences,
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Manabe Noboru
Graduate School Of Agricultural And Life Sciences Univ. Of Tokyo
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Manabe Noboru
Graduate School Of Agricultural And Life Sciences University Of Tokyo
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Manabe Noboru
Unit Of Anatomy And Cell Biology Department Of Animal Sciences Kyoto University
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NAGAO Masaya
Graduate School of Biostudies, Kyoto University
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Manabe Noboru
Animal Resource Science Center The University Of Tokyo
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Nishimura Shotaro
Faculty Of Agriculture Graduate School Kyushu University
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Nagao M
Graduate School Of Biostudies Kyoto University
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NISHIHARA Susumu
Unit of Anatomy and Cell Biology, Department of Animal Sciences, Kyoto University
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Manabe Noboru
Animal Resource Sci. Center Graduate School Of Agricultural And Life Sciences The Univ. Of Tokyo
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Miyamoto Hajime
Dept. of Animal Sciences, Kyoto University
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Miyamoto H
Department Of Animal Sciences Kyoto University
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Nakayama Mizuho
Unit Of Anatomy And Cell Biology Department Of Animal Sciences Kyoto University
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Miyamoto Hajime
Unit Of Anatomy And Cell Biology Department Of Animal Sciences Kyoto University
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