ウシの卵胞におけるinhibin α-subunitのステージ特異的な分布と卵胞液中の各種ホルモンレベルについて
スポンサーリンク
概要
- 論文の詳細を見る
The changes in localization of inhibin α-subunit in bovine ovarian follicles during follicular development were assessed by immunohistochemical staining with monoclonal anti-inhibin α-subunit antibody. The changes in inhibin, estradiol-17β (E2), progesterone (P) and testosterone (T) levels in the follicular fluid during follicular development were also investigated. The follicles obtained from the bovine ovaries in mid-luteal stage were histologically classified into 7 stages. Stages I, II and III were growing healthy follicles, and stages IV, V, VI and VII were atretic follicles. In both growing and atretic follicles, inhibin α-subunit were histochemically demonstrated in the granulosa cells. Strong or moderate immunostaining for inhibin α-subunit were found only in the granulosa cells of stages II and III follicles (the strongest staining was found in stage III), and trace staining was seen in a small number of theca interna cells of stages II and III follicles. The granulosa cells of early atretic follicles (stage IV) also have the ability to produce and secrete inhibin, but finally they lost the ability. No positive staining was demonstrated in any cells of progressed atretic follicles (stage V, VI and VII). Inhibin level in the follicular fluid was higher in the growing follicles (highest level at stage II) than in the atretic follicles. Follicular fluid E2 level increased from stages I to III, but decreased from stage IV onward. The P levels remained low from stages I to VI, but increased only in stage VII. The T levels in stages III and VII were lower than in the other stages. Follicular fluid inhibin level were related to E2 level but not P or T levels. In conclusion, the inhibin α-subunit is produced by follicular granulosa cells in growing follicles of the bovine ovaries, and inhibin may stimulate E2 secretion in growing but not in atretic follicles.
- 日本繁殖生物学会の論文
著者
-
Kitamura Nobuo
Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine
-
HONDO Eiichi
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
-
Yamada Junzo
Department Of Veterinary Anatomy Obihiro University Of Agriculture And Veterinary Medicine
-
Hasegawa Yoshitaka
Laboratory of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Kobe Gakuin University
-
Manabe Noboru
Unit Of Anatomy And Cell Biology Department Of Animal Sciences Kyoto University
-
MIYAMOTO AKIO
Laboratory of Animal Genetics and Reproduction, Department of Animal Science, Obihiro University of
-
Yoshimura Shuichi
Department of Veterinary Anatomy
-
Murabayashi Hiroshi
Department of Veterinary Anatomy
関連論文
- Spontaneous Endometrial Hyperplasia in the Uteri of IL-2 Receptor Beta-Chain Transgenic Mice
- Papillary Fibroelastoma of the Aortic Valve : Evaluation with Transesophageal Echocardiography and Magnetic Resonance Imaging
- Strategies for a Schizophrenic Patient Who Required Aortic Valve Replacement
- A Novel Technique for Removal of Permanent Pacemaker Leads
- Impact of Myocardial Angiotensin-Converting Enzyme Activity on Coronary Vascular Resistance and Serum Brain Natriuretic Peptide Concentration in Coronary Bypass Surgery
- ブタ卵胞顆粒層細胞アポトーシスにおけるTRAILシグナル経路の役割
- マウス胎仔の器官形成期におけるRARαおよびRXRα mRNAの発現におよぼす低用量ビスフェノールAの影響
- 老化促進マウスにおける黄体退行異常:Fas Ligand/Fas依存性アポトーシスシグナル伝達因子の発現について
- ブタ卵巣の卵胞閉鎖における顆粒層細胞アポトーシス誘導にTRADDが必要である
- ブタ卵巣の閉鎖卵胞顆粒層細胞ではTRAIL囮受容体-1が消失する
- ブタ卵胞顆粒層細胞膜上の抗原を認識するモノクローナル抗体
- ウシおよびブタ卵巣における卵胞退行に伴う1、3および4型コラーゲンおよびこれらのmRNA局在の変化
- 老化促進モデルマウス(SAM)卵巣における黄体の異常蓄積
- ブタおよびウシ卵胞退行中の顆粒層および内卵胞膜細胞におけるアポトーシス細胞局在の種差について
- ブタ卵胞退行過程における細胞接着因子の推移
- IGF-I過剰発現はマウス胎盤形成期に流産を引き起こす
- Elevation of Brain Natriutetic Peptide in Pericardia! Fluid in Patients with Postoperative Atrial Fibrillation Undergoing Off-Pump Coronary Artery Bypass Surgery
- Altered Expression of Nuclear Receptors Affects the Expression of Metabolic Enzymes and Transporters in a Rat Model of Cholestasis
- Left Ventricular Outflow Tract Obstruction Due to Anomalous Insertion of Papillary Muscle
- Competitive Enzyme Immunoassay for Bovine Growth Hormone
- ブタの着床時の卵管と子宮内膜における上皮成長因子受容体、血管内皮成長因子受容体、線維芽細胞成長因子受容体の発現
- THE WEIGHT AND THE HISTOLOGICAL CHANGES WITH AGE OF THE BURSA OF FABRICIUS IN CHICKENS
- 非繁殖季節のめん羊における異なる3種の発情・排卵誘起法の比較
- ラットSKD3 cDNAのクローニングと精巣におけるSKD3の発現
- ラット精巣において、プロラクチンはプロタミン2mRNAの発現を誘導する
- ヤギ下垂体における塩基性線維芽細胞成長因子の局在に関する免疫組織化学的研究
- Effect of Human Erythropoietin (hEPO) Treatment on Anemia in ICR-derived Glomerulonephritis (ICGN) Mice
- ホルスタイン種雄牛の加齢にともなう血中ホルモン濃度の変化
- Principal Component Analysis of the Common Tree Shrew Skulls from Laos, Thailand and Malaysia
- The functional anatomy of the masticatory muscles of the Malayan pangolin, Manis javanica
- 未成熟マウス子宮においてカルシウム結合タンパク(CaBP-9k)の転写と翻訳は性ステロイドホルモンとその受容体によって特異的に制御される
- ウシ胎子卵巣における前胞状卵胞の発育と血中ホルモン濃度の動態
- ウマの卵胞発育過程におけるインヒビン/アクチビンサブユニット,アロマターゼおよび3β-ヒデロキシステロイド脱水素酵素の発現
- Distribution of cardiac musculature in the pulmonary venous wall of three species of the genus Mustela
- Extrapericardial Pulmonary Vein Clamp Technique for Pulmonary Arteriovenous Fistula : Report of a Case
- Protective Effect of N-methyl-l-deoxynojirimycin on Lung Ischemia Reperfusion Injury : An in vivo Study : MdNM Reduces Lung Ischemia Reperfusion Injury
- ブタ退行卵胞顆粒層細胞における細胞外マトリックスとアポトーシスの相互作用
- Ultrastructural Changes in Granulosa Cells in Porcine Antral Follicles Undergoing Atresia Indicate Apoptotic Cell Death
- Alterations in Cell Proliferation and Morphology of Ampullar Epithelium of the Mouse Oviduct during the Estrous Cycle
- ブタ卵胞顆粒層細胞の新規なアポトーシス受容体と囮受容体を認識するモノクローナル抗体
- Immunohistochemical Quantification of Fast-Myosin in Upper Hind Limb Muscles of the Pig
- Examination of Granulosa Cell Glycoconjugates Which Change During Follicular Atresia in the Pig Ovary
- Histology of Vermiform Appendix-Like Organ in Slow Loris
- Histological Study on Intestinal Diverticulum of Tree Shrew (Tupaia Javanica)
- SURGICAL TRETMENT OF THE COMBINED VALVULAR HEART DISESE. : LATE PRESULTS OF THE CASAES WITH UNTEREATED ASSOCIATED VALVULAR LESION : Cardiac Surgery I : IInd Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 19
- A Simple Superovulation Method of A Single Injection of Follicle- Stimulating Hormone Combined with Equine Chorionic Gonadotropin for Superovulation of Suffolk Ewes During the Breeding Season: I. Effects of Different Treatments on the Endocrine Profiles
- Scanning Electron Microscopic Observation of Apical Sites of Open-Type Paraneurons in the Stomach, Intestine and Urethra
- ウシの卵胞におけるinhibin α-subunitのステージ特異的な分布と卵胞液中の各種ホルモンレベルについて
- Age-Related Changes in the Serum Levels of Inhibin, FSH, LH and Testosterone in Holstein Bulls
- Histological Study of Granulated Metrial Gland (GMG) Cells in Beige (DA-bg/bg) Rats
- Localization of Interleukin-6 Receptor mRNA in the Pregnant and Non-pregnant Mouse Uterus
- Differential Transcriptional and Translational Regulations of Calbindin-D_ by Steroid Hormones and Their Receptors in the Uterus of Immature Mice
- Changes in Cell Adhesion Molecules during Follicular Atresia in Porcine Ovaries
- MORPHOLOGY OF BURSA OF FABRICIUS IN BURSECTOMIZED AND THYMECTOMIZED DUCKS
- A Simple Superovulation Method of A Single Injection of Follicle-Stimulating Hormone Combined with Equine Chorionic Gonadotropin for Superovulation of Suffolk Ewes During the Breeding Season: II. The Ovarian Responses and the Embryo Qualities
- 過剰排卵誘起された雌羊における異常黄体の発生
- Effects of Oral Exposure of Bisphenol A on mRNA Expression of Nuclear Receptors in Murine Placentae Assessed by DNA Microarray
- Functional, Metabolic, and Histological Changes of Vascular Tissues after Warm Ischemia
- Agrin Pathway is Controlled by Leukemia Inhibitory Factor (LIF) in Murine Implantation
- Upregulation of Indian Hedgehog Gene in the Uterine Epithelium by Leukemia Inhibitory Factor During Mouse Implantation
- ジャワオオコウモリおよびコキクガシラコウモリの精巣組織におけるレクチン反応性
- Effect of Single or Multiple Injection of Follicle Stimulating Hormone Combined with Pregnant Mare Serum Gonadotropin on Superovulatory Response, and Normal and Freezable Embryos in Ewes
- Thoracic Surgery Residency Program and Health Care System in the United States
- IGF-I過剰発現はマウス胎盤形成期に流産を引き起こす
- ウシの卵胞におけるinhibin α-subunitのステージ特異的な分布と卵胞液中の各種ホルモンレベルについて
- Prolactin Induces Protamine 2mRNA Expression in Rat Testis
- Morphological Studies on Testicular Development in the Horse
- Local Release of Progesterone and Oxytocin from Microdialyzed Corpus Luteum in Superovulated Ewes : Characterization during the Non-breeding Season
- A Simple Superovulation Method of A Single Injection of Follicle-Stimulating Hormone Combined with Equine Chorionic Gonadotropin for Superovulation of Suffolk Ewes During the Breeding Season : II. The Ovarian Responses and the Embryo Qualities
- A Simple Superovulation Method of A Single Injection of Follicle-Stimulating Hormone Combined with Equine Chorionic Gonadotropin for Superovulation of Suffolk Ewes During the Breeding Season : I. Effects of Different Treatments on the Endocrine Profiles
- Relationships Among Follicular Fluid Estradiol-17β Concentration, Morphology of Cumulus-Oocyte Complex and Developmental Capacity of Individually Matured, Fertilized and Cultured Bovine Oocytes In Vitro
- Ultrastructural Changes in Granulosa Cells in Porcine Antral Follicles Undergoing Atresia Indicate Apoptotic Cell Death
- Alterations in Cell Proliferation and Morphology of Ampullar Epithelium of the Mouse Oviduct during the Estrous Cycle
- ブタおよびウシ卵胞退行中の顆粒層および内卵胞膜細胞におけるアポトーシス細胞局在の種差について
- Examination of Granulosa Cell Glycoconjugates Which Change During Follicular Atresia in the Pig Ovary
- ブタの着床時の卵管と子宮内膜における上皮成長因子受容体、血管内皮成長因子受容体、線維芽細胞成長因子受容体の発現
- ベージュ(DA-bg/bg)ラットの顆粒間膜腺(GMG)細胞の組織学的研究
- 妊娠および非妊娠マウス子宮におけるIL-6受容体mRNAの局在
- Morphological Study on Pigmented Cells in the Horse Testis.
- Localization of Proliferative and Apoptotic Cells in the Kidneys of ICR-Derived Glomerulonephritis(ICGN) Mice.
- Characteristics of Lectin Staining Patterns Assessed by a Modified Sensitive Thermo-Method in Rat Livers with Heterologous Serum-Induced Fibrosis.