ベージュ(DA-bg/bg)ラットの顆粒間膜腺(GMG)細胞の組織学的研究
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概要
- 論文の詳細を見る
To clarify the roles of granulated metrial gland (GMG) cells for successful pregnancy in rats, GMG cells in beige rats (genotype: DA-bg/bg), whose NK cells show lysosomal dysfunction because of abnormalities in cytoplasmic granules, were examined in mid- and late-pregnancy by light and electron microscopies. The GMG cells of beige rats were significantly less in number than those of the two controls (genotypes: DA-bg/+ and DA-+/+) in mid-and late-pregnancy, and this accompanied a low reproductive performance in the beige rats. The size of intracellular granules in the GMG cells of the beige rats was larger than for the two controls on each corresponding day of pregnancy. These results suggest that the activity of rat GMG cells and peripheral NK cells might be influenced by the beige gene, which is involved in reproductive performance.
- 日本繁殖生物学会の論文
著者
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HONDO Eiichi
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
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本道 栄一
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
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Kiso Yasuo
Department Of Veterinary Anatomy Faculty Of Agriculture Yamaguchi University
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Nakamuta Nobuaki
First Department Of Oral Anatomy Kyushu Dental College
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KOKUBU Keiji
The United Graduate School of Veterinary Science, Yamaguchi University
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Sagara Eiji
Animal Research Center Kyushu Dental College
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Nagahisa Ayusa
Department Of Veterinary Anatomy Faculty Of Agriculture Yamaguchi University
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Ozaki Kiyokazu
Faculty Of Pharmaceutical Science Research Institute Of Drug Safety Setsunan University
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國分 啓司
The United Graduate School of Veterinary Science, Yamaguchi University
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長久 アユサ
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
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