Exposure to Extremely Low Frequency Magnetic Fields Enhances Locomotor Activity via Activation of Dopamine D_1-Like Receptors
スポンサーリンク
概要
- 論文の詳細を見る
We demonstrated that exposure to extremely low frequency magnetic fields (ELF-MF) enhanced dopamine levels in the rat striatum. To extend our understanding, we examined the role of dopaminergic receptors in ELF-MF–induced behavioral changes. Exposure to ELF-MF (2.4 mT, 1 h/day, for one or seven days) enhanced locomotor activity in a time-dependent manner. This hyperlocomotor activity paralleled an increase in c-Fos-like immunoreactivity (c-Fos-IR). Pretreatment with SCH23390, a dopaminergic D1-like receptor antagonist, but not with sulpiride, a dopaminergic D2-like receptor antagonist, inhibited ELF-MF–induced increased locomotor activity and c-Fos-IR. Thus, our results suggest that ELF-MF–induced behavioral responses are, at least in part, mediated by activation of dopamine D1-like receptors.
- 社団法人 日本薬理学会の論文
- 2007-12-20
著者
-
SHIN Eun-Joo
Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University
-
JEONG Ji
Department of Pharmacology, Chung-Ang University
-
KIM Hyoung-Chun
Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University
-
YAMADA Kiyofumi
Department of Neurosurgery, Graduate School of Medicine, Gifu University
-
Nabeshima Toshitaka
Department of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Meijo University, J
-
Kim Hyoung-chun
Neuropsychopharmacology And Toxicology Program College Of Pharmacy Kangwon National University
-
Kim Hyoung-chun
Neuropsychopharmacology And Toxicology Program Coll. Of Pharmacy Kangwon National Univ.
-
Kim Hyoung-chun
Neuropsychopharmacology And Toxicology Program Coll. Of Pharmacy Kangwon National Univ. Kor
-
Yamada Kiyofumi
Department Of Hospital Pharmacy Nagoya University School Of Medicine
-
KIM Hyun
Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University
-
JANG Choon-Gon
Department of Pharmacology, College of Pharmacy, Sungkyunkwan University
-
Nabeshima Toshitaka
Department Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Meijo University
-
Nabeshima Toshitaka
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Meijo University
-
Yamada Kiyomi
Department Of Neuropsychopharmacology And Hospital Pharmacy Nagoya University Graduate School Of Med
-
Jhoo Jin
Department Of Pharmacology Chung-ang University
-
Jang Choon-gon
Department Of Pharmacology College Of Pharmacy Sungkyunkwan University
-
Yamada K
Department Of Neuropsychopharmacology And Hospital Pharmacy Nagoya University Graduate School Of Med
-
Shin Eun-joo
Neuropsychopharmacology And Toxicology Program College Of Pharmacy Kangwon National University
-
Jeong Ji
Department Of Pharmacology College Of Medicine Chung-ang University
-
Jeong Ji
Department of Pathology, Kyungpook National University Medical Center, 474 Hakjeongdong, Buk-gu, Daegu 702-210, Republic of Korea
関連論文
- Decrease in the Kainate-Induced Wet Dog Shake Behavior in Genetically Epilepsy-Prone Rats : Possible Involvement of an Impaired Synaptic Transmission to the 5-HT_ Receptor
- Growth Hormone-Releaser Diet Attenuates β-Amyloid(1-42)-Induced Cognitive Impairment via Stimulation of the Insulin-Like Growth Factor (IGF)-1 Receptor in Mice
- Parishin C Attenuates Phencyclidine-Induced Schizophrenia-Like Psychosis in Mice: Involvements of 5-HT1A Receptor
- Convulsion During Intra-arterial Infusion of Fasudil Hydrochloride for the Treatment of Cerebral Vasospasm Following Subarachnoid Hemorrhage
- Mutations Leu427, Asn428, and Leu431 Residues within Transmembrane Domain-I-Segment 6 Attenuate Ginsenoside-Mediated L-Type Ca2+ Channel Current Inhibitions
- Danthron Inhibits the Neurotoxicity Induced by Various Compounds Causing Oxidative Damages Including β-Amyloid (25-35) in Primary Cortical Cultures (Toxicology)
- High Power Operations of 980 nm Ga_In_As/Ga_xIn_As_yP_/Ga_In_P/GaAs Pump Lasers Prepared by Multi-step Metalorganic Vapor Phase Epitaxial Growth with Ion Implanted Channels
- Klotho 遺伝子変異マウスの学習障害と酸化ストレス
- Effects of Dietary Vegetable Oils on Behavior and Drug Responses in Mice
- 22B-10-4 Analysis of morphine dependence mechanism using cyclic AMP responsive element binding protein binding protein (CBP) mutation mice.
- 高カロリー輸液施行時の家兎における酸代謝に対する塩酸および酢酸の影響
- Neuropsychotoxicity of Abused Drugs : Potential of Dextromethorphan and Novel Neuroprotective Analogs of Dextromethorphan With Improved Safety Profiles in Terms of Abuse and Neuroprotective Effects
- Exposure to Extremely Low Frequency Magnetic Fields Enhances Locomotor Activity via Activation of Dopamine D_1-Like Receptors
- Growth Hormone Releaser Attenuates β-Amyloid (1-42)-Induced Memory Impairment in Mice
- PAP 9704, a Korean Herbal Medicine Attenuates Methamphetamine-Induced Hyperlocomotion via Adenosine A_ Receptor Stimulation in Mice(Pharmacology)
- Synergistic Effects of Adenosine A_ Antagonist and L-DOPA on Rotational Behaviors in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Mouse Model
- Effect of Dietary Fiber on Morphine-induced Constipation in Rats(Food & Nutrition Science)
- Superficial Temporal Artery to Middle Cerebral Artery Double Bypass Via a Small Craniotomy : —Technical Note—
- Evaluation of Interleukin-2 mRNA in Whole Blood as a Parameter for Monitoring Cyclosporine Pharmacodynamics(Pharmacology)
- Characteristics of Superluminescent Diodes Utilizing In_Ga_As Quantum Dots
- Clozapine Prevents a Decrease in Neurogenesis in Mice Repeatedly Treated With Phencyclidine
- Angioplasty and Stenting of Totally Occluded Common Carotid Artery at the Chronic Stage : Case Report
- Orally Active NGF Synthesis Stimulators : Potential Therapeutic Agents in Alzheimer's Disease.
- Structure-Related Pharmacokinetics of Xanthines after Direct Administration into the Peritoneal Cavity of Rats
- Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes
- DESIGN OF A PHENCYCLIDINE IMPLANTATION PELLET : SUITABLE FOR TOLERANCE DEVELOPMENT
- MECHANISM OF TOLERANCE DEVELOPMENT TO PHENCYCLIDINE IN RELATION TO GABA-ERGIC NEURONAL AND DISPOSITIONAL FUNCTIONS IN MICE
- Molecular Mechanism of Cholinergic Dysfunction and Cognitive Deficits Induced by Amyloid β-Peptide
- Tissue Plasminogen Activator Is Not Involved in Methamphetamine-Induced Neurotoxicity
- Neuropsychotoxicity of Abused Drugs : Involvement of Matrix Metalloproteinase-2 and -9 and Tissue Inhibitor of Matrix Metalloproteinase-2 in Methamphetamine-Induced Behavioral Sensitization and Reward in Rodents
- Tissue Plasminogen Activator (t-PA) Is Involved in Morphine-Induced Rewarding Effects
- Superficial Temporal Artery to Middle Cerebral Artery Double Bypass Via a Small Craniotomy : Technical Note
- The role of N-methyl-D-aspartate receptors in development of morphine dependence in mice (NEREVOUS SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Comparative Absorption of 5-Aminosalicylic Acid(5-ASA)after Administration of a 5-ASA Enema and Salazosulfapyridine(SASP)after an SASP Suppository in Japanese Volunteers
- Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats.
- DOSE-DEPENDENT PHARMACOKINETICS OF ENPROFYLLINE IN RATS
- The Roles of Glial Cell Line-Derived Neurotrophic Factor, Tumor Necrosis Factor-α, and an Inducer of These Factors in Drug Dependence
- Prophylaxis of Local Vascular Graft Infection with Levofloxacin Incorporated into Albumin-Sealed Dacron Graft (LVFX-ALB Graft)
- Prevention of Vascular Graft Infection by Sisomicin Incorporated into Fibrin Glue
- Effects of Quercetin on Human α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor-Mediated Ion Currents
- Effects of Nicotine on Stress Response in Mice
- DEVELOPMENT OF AMNESIA MODEL FOR SCREENING OF NOOTROPIC DRUGS AND EFFECTS OF MEVALONIC-GABA ON LEARNING AND MEMORY IN MICE
- Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats
- S5-4 Psychobehavioral deficits induced by a non-competitive N-methyl-D-aspartate receptor antagonist and signal transduction through N-methyl-D-aspartate receptors(SYMPOSIUM 5: PHYSIOLOGY AND DISEASE OF GLUTAMATE IN NEURONAL AND GLIAL CELLS)(Proceedings o
- Elimination Kinetics of Quinaprilat and Perindoprilat in Hypertensive Patients with Renal Failure on Haemodialysis
- Conditioned Suppression of Motility : Possibility for Evaluation of Learning and Memory in Mice
- TOXICITY OF β-AMYLOID PEPTIDE
- Impairments of Long-term Potentiation in Hippocampal Slices of Beta-amyloid-infused Rats.
- DOPAMINERGIC INVOLVEMENT IN PHENCYCLIDINE-INDUCED STEREOTYPED BEHAVIOR
- Perspectives of Pharmacotherapy in Alzheimer's Disease
- A survey of antipsychotic polypharmacy in outpatients at Nagoya University Hospital
- The Necessity of Adjusting the Dosage of Zonisamide When Coadministered with Other Anti-epileptic Drugs
- Parishin C Attenuates Phencyclidine-Induced Schizophrenia-Like Psychosis in Mice : Involvements of 5-HT_ Receptor
- Basic and Translational Research on Proteinase-Activated Receptors : Regulation of Nicotine Reward by the Tissue Plasminogen Activator (tPA) : Plasmin System via Proteinase-Activated Receptor 1
- Drug Dependence, Synaptic Plasticity, and Tissue Plasminogen Activator
- Up-regulation of cAMP, but not voltage-sensitive calcium ion channels is involved in the inhibitory effects of nefiracetam on methamphetamine-induced discriminative responses
- Changes in Ciliary Neurotrophic Factor Content in the Rat Brain after Continuous Intracerebroventricular Infusion of β-Amyloid(1-40)Protein
- Memory Impairment in Rats Induced by an Active Fragment of Nerve Growth Factor Antibody.
- IMPAIRMENT OF ACTIVE AVOIDANCE RESPONSE IN RATS WITH CONTINUOUS INFUSION OF QUINOLINIC ACID INTO THE LATERAL VENTRICLE
- Recovery and Maintenance of Copper Levels in Geriatric Patients on Enteral Feeding for a Prolonged Period
- EFFECTS OF CATECHOLAMINERGIC OR TRYPTAMINERGIC AGENTS ON THE MORPHINE-INDUCED STRAUB TAIL REACTION
- An Environmental and Biological Study of Occupational Exposure to Cyclophosphamide in the Pharmacy of a Japanese Community Hospital Designated for the Treatment of Cancer
- Aged-Related Changes in Learning and Memory, Choline Acetyltransferase Activity and Number of Neuronal Cells in Rats
- Amyloid Pathology and Protein Kinase C (PKC) : Possible Therapeutics Effects of PKC Activators
- Brain-Derived Neurotrophic Factor/TrkB Signaling in Memory Processes
- Endogenous Modulators for Drug Dependence
- CONDITIONED SUPPRESSION AND OPIOID KAPPA RECEPTOR IN MICE
- Neuropsychotoxic and Neuroprotective Potentials of Dextromethorphan and Its Analogs
- Role of Catecholaminergic and Cyclic AMP Systems in Psychological Dependence on Phencyclidine: A Study in Mutant Mice
- Skin Tests of a Novel Nicotine Patch, PHK-301p, in Healthy Male Volunteers : Phase I, Placebo-Controlled Study
- S9-2 Anti-addictive and pro-addictive substances commonly involved in methamphetamine and morphine dependence(SYMPOSIUM 9: MOLECULAR MECHANISMS OF DRUG DEPENDENCE)(Proceedings of the 31st Annual Meeting)
- PRO-ADDICTIVE AND ANTI-ADDICTIVE FACTORS FOR DRUG DEPENDENCE
- OTOTOXICITY INDUCED BY PRE-AND POSTNATAL EXPOSURE TO AMINOGLYCOSIDE ANTIBIOTICS
- NEUROTOXICITY OF CARBON MONOXIDE IN CENTRAL NERVOUS SYSTEM
- The High Atherosclerotic Risk Among Epileptics : the Atheroprotective Role of Multivitamins
- ROLE OF DOPAMINERGIC AND SEROTONERGIC NEURONAL SYSTEMS IN THE PREFRONTAL CORTEX OF RATS IN PHENCYCLIDINE-INDUCED BEHAVIORS
- ROLE OF DOPAMINERGIC AND GABAERGIC MECHANISMS IN DISCRETE BRAIN AREAS IN PHENCYCLIDINE-INDUCED LOCOMOTOR STIMULATION AND TURNING BEHAVIOR
- INVOLVEMENT OF OPIOID RECEPTORS IN HYPO- AND HYPER-THERMIC EFFECTS INDUCED BY PHENCYCLIDINE IN MICE
- EFFECTS OF DIFENAMIZOLE ON CONTENT OF CATECHOLAMINES AND METABOLITES IN MOUSE BRAIN
- Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo
- CORRELATION BETWEEN THE 5-HYDROXYTRYPTAMINE CONTENTS IN THE BRAIN AND DEGREES OF SENSORY, AND LOCOMOTOR ACTIVITIES IN THE RAT
- Neuropsychotoxic and Neuroprotective Potentials of Dextromethorphan and Its Analogs
- Effects of Kamikihito, a Traditional Chinese Medicine, on Neurotransmitter Receptor Binding in the Aged Rat Brain Determined by In Vitro Autoradiography (2): Changes in GABAA and Benzodiazepine Receptor Binding
- Vulnerability in Early Life to Changes in the Rearing Environment Plays a Crucial Role in the Aetiopathology of Psychiatric Disorders
- 薬物乱用の神経心理毒性学
- Effects of Obstacle Crossing on Dynamic Postural Control of Parkinson's Disease Patients
- Tai Chi and Its Effects on Dynamic Postural Control in the Initiation of Gait by Older People
- D-Serine Ameliorates Neonatal PolyI:C Treatment–Induced Emotional and Cognitive Impairments in Adult Mice
- Reliability and Validity of the Japanese Version of BEMIB Modified for Patients With Bipolar Disorder: a Self-rating Scale for Medication Adherence
- Effects of BMY-21502 on Anoxia in Mice.
- Animal Model for Schizophrenia That Reflects Gene-Environment Interactions
- Effects of Risperidone on Phencyclidine-Induced Behaviors: Comparison with Haloperidol and Ritanserin.
- Effects of Ginsenoside Rg3 on α9α10 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
- Effects of Kamikihito, a Traditional Chinese Medicine, on Neurotransmitter Receptor Binding in the Aged Rat Brain Determined by In Vitro Autoradiography (1): Changes in the (3H)QNB Binding.
- Neuropharmacological Characterization of Voltage-Sensitive Calcium Channels: Possible Existence of Neomycin-Sensitive, .OMEGA.-Conotoxin GVIA- and Dihydropyridines-Resistant Calcium Channels in the Rat Brain.
- Effects of Nerve Growth Factor(NGF) in Rats with Basal Forebrain Lesions.
- Anticancer Effects of Adriamycin-Loaded Hydroxyapatite Implants Determined in a Swarm Rat Chondrosarcoma Model.
- Antitumor Effects and Distribution of Adriamycin Incorporated into Hydroxyapatite Implants in a Cancer Rat Model Bearing Swarm Rat Chondrosarcoma.
- Characteristics of Transient Cerebral Ischemia-Induced Deficits on Various Learning and Memory Tasks in Male Mongolian Gerbils.
- D-Serine Ameliorates Neonatal PolyI:C Treatment-Induced Emotional and Cognitive Impairments in Adult Mice