In Vitro Alpha-glucosidase Inhibitory Effect of Zn (II) Complex with 6-Methyl-2-picolinmethylamide

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概要

• 論文の詳細を見る

• We found alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide (6mpa-ma) which showed the highest blood glucose lowering effect in Zn(II) complexes with picolinamide derivatives in KK-A^y mice. The Zn(II) complex showed strong alpha-glucosidase inhibitory activity greater by about eighty times (substrate : maltose) and forty times (substrate : sucrose) compared with acarbose.

• 公益社団法人日本薬学会の論文
• 2005-04-01

著者

• SAKURAI Hiromu

  Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University

• YOSHIKAWA Yutaka

  Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University

• KOJIMA Yoshitane

  Department of Chemistry, Graduate School of Science, Osaka City University

• Ueda Eriko

  Department Of Chemistry Graduate School Of Science Osaka City University

• Sakurai Hiromu

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• Sakurai H

  Kyoto Pharmaceutical Univ. Kyoto Jpn

• Kajiwara Naemi

  Laboratory Of Nutrition Physiology Graduate School Of Life Science Kobe Women's University

• KAJIWARA Naemi

  Graduate School of Home Economics, Kobe Woman's University

• Kojima Y

  Department Of Chemistry Graduate School Of Science Osaka City University

• Kojima Yoshitane

  Department Of Chemistry Faculty Of Science Osaka City University

• UEDA Eriko

  Graduate School of Life Science, Kobe Women's University

• Yoshikawa Yutaka

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• Ueda Eriko

  Laboratory of Nutrition Physiology, Graduate School of Life Science, Kobe Women's University

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