Structural studies of cyclo(L-histidyl-L-histidyl) and its metal complexes.
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概要
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The crystal structure of cyclo(L-histidyl-L-histidyl) was determined by X-ray diffraction techniques, and was refined to a final <I>R</I> index of 0.066 for 680 reflections. This showed that one imidazolyl group of this compound faces the piperazine ring(folded) whereas the other is kept away from the ring(unfolded). A calculation using the α-β coupling-constant data of this peptide obtained by an <SUP>1</SUP>H NMR measurement shows that the ratio of a folded conformation to an unfolded one is 49:51 in D<SUB>2</SUB>O. Also, NMR investigations of zinc(II) and silver(I) complexes with this peptide were carried out in D<SUB>2</SUB>O.
- 公益社団法人 日本化学会の論文
著者
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Hirotsu Ken
Department Of Chemistry Faculty Of Science Osaka City University
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Kojima Yoshitane
Department Of Chemistry Faculty Of Science Osaka City University
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Yamashita Tetsushi
Department Of Chemistry Faculty Of Science Osaka City University
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Higuchi Taiichi
Department Of Chemistry Faculty Of Science Osaka City University
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Nishide Shinya
Department of Chemistry, Faculty of Science, Osaka City University
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