Analyses of the Metallothioneins and Trace Metals in the Liver and Serum of the Patients with Hepatocellular Carcinoma

スポンサーリンク

概要

• 論文の詳細を見る
• 2004-12-31

著者

• Saisho H

  Department Of Medicine And Clinical Oncology Graduate School Of Medicine Chiba University

• Kubo Kanenobu

  Department Of Physical Chemistry Faculty Of Pharmaceutical Sciences Kinki University

• FUKUDA Hiroyuki

  First Department of Medicine, School of Medicine, Chiba University

• EBARA Masaaki

  First Department of Medicine, School of Medicine, Chiba University

• Ebara M

  First Department Of Medicine School Of Medicine Chiba University

• Ebara Masaaki

  First Department Of Medicine Chiba University School Of Medicine

• Fukuda H

  Chiba Univ.

• Sakurai Hiromu

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• Nakayama A

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• Minami T

  Osaka Univ. Osaka Jpn

• Minami T

  Department Of Science And Technology Kinki University

• Minami Takeshi

  Department Of Biotechnology Graduate School Of Engineering Osaka University

• Fukuda Hiroyuki

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• KAWATA Takumi

  Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University

• NAKAYAMA Akihiro

  Gifu Keizai University

• Nakamura Shunsuke

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• Enomoto Shuichi

  Multitracer Research Group Cyclotron Center Riken

• Kawata Takumi

  Department Of Analytical And Bioinorganic Chemistry Kyoto Pharmaceutical University

• NAKAYAMA Akihiro

  Multitracer Research Group, Radioisotope Technology Division, Cyclotron Center

• Kubo K

  Department Of Physical Chemistry Faculty Of Pharmaceutical Sciences Kinki University

• Enomoto Shuichi

  Multitracer Research Group Radioisotope Technology Division Cyclotron Center

• MINAMI TAKESHI

  Department of Biochemistry, Faculty of Pharmaceutical Sciences, University of Tokushima

• NAKAYAMA Akihiro

  Department of Physics, Nagoya University

関連論文

• Secretory Transport of Methylprednisolone Possibly Mediated by P-Glycoprotein in Caco-2 Cells
• Defferent Absorption Behaviors among Steroid Hormones Due to Possible Interaction with P-Glycoprotein in the Rat Small Intestine
• Mononuclear to Tetranuclear Structural Transformation in Vanadyl Complexes of 3-Hydroxypyridine-2-carboxylic Acid (H_2hpic)
• Breaks in Double-Strand DNA by Cu(II) Complexes of Etoposide (VP-16) and Its Derivatives, as Evaluated by S1 Nuclease Treatment
• Identification of metallothionein isoforms with capillary zone electrophoresis using a polyacrylamide-coated tube
• Immunohistochemical Study of Transforming Growth Factor-β1, Matrix Metalloproteinase-2, 9, Tissue Inhibitors of Metalloproteinase-1, 2, and Basement Membrane Components at Pancreatic Ducts in Chronic Pancreatitis
• BILIARY STENTING FOR MALIGNANT BILIARY OBSTRUCTION
• Evaluation of Distribution Patterns for Copper and Zinc in Metallothionein and Superoxide Dismutase in Chronic Liver Diseases and Hepatocellular Carcinoma Using High-Performance Liquid Chromatography(HPLC)(Analytical Biochemistry)
• Antidiabetic Activity of Zn(II) Complexes with a Derivative of L-Glutamine
• Insulinomimetic Zinc(II) Complexes with Natural Products: In Vitro Evaluation and Blood Glucose Lowering Effect in KK-A^y Mice with Type 2 Diabetes Mellitus
• Catalytic and Spectroscopic Properties of Imidazole(N)-Fe(III)porphyrin Complexes in Dioxygenation of Tryptophan Derivatives
• Superoxide Dismutase Mimetic Complex of Mn (II)/N, N-Bis (2 - Pyridylmethyl) - (S) - Histidine
• Immunohistochemical metallothionein expression in hepatocellular carcinoma : relation to tumor progression and chemoresistance to platinum agents
• Immunohistochemical Localization of Type IV Collagen α Chains in the Basement Membrane of the Pancreatic Duct in Human Normal Pancreas and Pancreatic Diseases
• Characterization of hyperplastic foci observed in surgical specimens of hepatocellular carcinoma
• Scavenging Activities of α-, β- and γ-Thujaplicins against Active Oxygen Species
• New Zinc (II) Complexes with Tetradentate Amino Acid Derivatives: Structure Characterization, Solution Chemistry, and in vitro Insulinomimetic Activity
• New Insulinomimetic Zinc(II)Complexes of α-Amino Acids and Their Derivatives with Zn(N_2O_2)Coordination Mode
• Selenium Supplementation Rescues Cardiac Output in Patients with Severe Heart Failure who are Intractable to ACE Inhibitors and β-Blockers(Heart Failure, Clinical 14 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• A New Physiologically Based Pharmacokinetic Analysis for In Vivo Organ Disposition of Nitroxyl Spin Probes in Mice as Measured by Multisite Detection L-band ESR (MSD-LESR)
• Roles of γ-Aminobutyric Acid_B (GABA_B) and γ-Hydroxybutyric Acid Receptors in Hippocampal Long-Term Potentiation and Pathogenesis of Absence Seizures
• Pharmacological profiles of generalized absence seizures in lethargic, stargazer and γ-hydroxybutyrate-treated model mice
• Role of oxidative stress on pathogenesis of hypertensive cerebrovascular lesions
• Relationship betweeen X- or L-Band ESR Spectra and Coordination Structures of Copper(II) Complexes with a CuO_4 Coordination Mode
• Coordination-Dependent ESR Spectra of Copper(II) Complexes with a CuN_4 Type Cooridnation Mode : Relationship between ESR Parameters and Stability Constants or Redox Potentials of the Complexes
• Oxovanadium(IV)-Porphyrin Complex as a Potent Insulin-Mimetic. Treatment of Experimental Type 1 Diabetic Mice by the Complex [meso-Tetrakis(4-sulfonatophenyl)porphyrinato]oxovanadate(IV)(4-)
• Merallokinetic Study of Zinc in the Blood of Normal Rats Given Insulinomimetic Zinc(II) Complexes and Improvement of Diabetes Mellitus in Type 2 Diabetic GK Rats by their Oral Administration
• Lysophosphatidylcholine Enhances Superoxide Anions Production via Endothelial NADH/NADPH Oxidase
• A Chemical Model of Tryptophan 2,3-Dioxygenase : Reactivity and Formation of a Reactive Intermediate in the Dioxygenation Processes
• A New Determination Method of Nitric Oxide (NO) with a NO-selective Electrode Demonstrated by the Kinetic Analysis of NO Generation and Decomposition
• Distinguishing Benign From Malinant Intraductal Papillary Mucinous Tumors of the Pancreas by Imaging Techniques
• Measurement of Acoustic Property Distributions of Diseased Heart and Liver Tissues
• Antioxidative Properties of Extracts from Ancient Rice Brans
• Novel screening method for ultraviolet protection : Combination of a human skin-equivalent model and 8-hydroxy-2'-deoxyguanosine
• Study of repeated arterial infusion chemotherapy with a subcutaneously implanted reservoir for advanced hepatocellular carcinoma
• Chemical Structure-Dependent Differential Effects of Flavonoids on the Catalase Activity as Evaluated by a Chemiluminescent Method(Analytical Biochemistry)
• An Improved Diagnostic Method for Chronic Hepatic Disorder : Analyses of Metallothionein Isoforms and Trace Metals in the Liver of Patients with Hepatocellular Carcinoma as Determined by Capillary Zone Electrophoresis and Inductively Coupled Plasma-Mass S
• Evaluation of Ultrasonic Fiber Structure Extraction Technique Using Autopsy Specimens of Liver
• The copper/zinc ratio in patients with hepatocellular carcinoma
• A New Diagnostic Method for Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma Based on Serum Metallothionein,Copper, and Zinc Levels
• Extraction of Quantitative Three-Dimensional Information from Ultrasonic Volumetric Images of Cirrhotic Liver
• Portal-systemic encephalopathy in two patients without liver cirrhosis and portal hypertension
• Synthesis, Structure, and In Vitro and In Vivo Insulinomimetic Activities of the Zinc(II)-6-Ethylpicolinate Complex
• New Bioactive Zinc(II) Complexes with Peptides and Their Derivatives : Synthesis, Structure, and In Vitro Insulinomimetic Activity
• New Insulinomimetic Zinc(II) Complexes of Nicotinamide and its Derivatives: X-ray Structure and Biochemical Activity
• A New Type of Orally Active Insulin-Mimetic Vanadyl Complex: Bis(l-oxy-2-pyridinethiolato)oxovanalum(IV)with VO(S_2O_2) Coordination Mode
• Evidence for Singlet Oxygen Involvement in Rat and Human Cytochrome P450-dependent Substrate Oxidations
• Oxovanadium (IV) and (V) Complexes with 3-Hydroxy-4(1H)-pyridinones and 1-Hydroxy-2(1H)-pyrimidinones - Synthesis, Structural Characteristics, and Their Insulin-mimetic Activities
• Insulinomimetic Vanadyl-Hydroxythiazolethione Complexes with VO(S_2O_2) Coordination Mode : The Correlation between the Activity and Hammett's Substituent Constant
• Synthesis of New Vanadyl Complexes of Hydroxyazine-type Heterocycles and Their Insulin-Mimetic Activities
• Zinc(II) complexes with allixin-derivatives as oral therapeutics for type 2 diabetes
• Insulinomimetic Activity of Vanadyl-Porphyrin Complexes
• A New Anti-diabetic Zn(II)-Hinokitiol (β-Thujaplicin) Complex with Zn(O_4) Coordination Mode
• A New Type of Orally Active Insulin-mimetic Vanadyl-porphyrin Complex : meso-Tetrakis({4-sulfonatophenyl}porphyrinato)oxovanadium(IV)
• Determination of trace element concentrations in ancient rices (red and black rices) and a present-day rice (Koshihikari) : Relationship among the trace element concentrations, species, harvest site and rice parts
• A Highly Potent Insulin-mimetic Zinc(II) Complex with a Zn(S_2O_2) Coordination Mode : Bis(1, 6-dimethyl-3-hydroxy-5-methoxy-2-pentyl-1, 4-dihydropyridine-4-thionato)zinc(II)
• Insulin-Mimetic Vanadyl (IV) Complexes as Evaluated by Both Glucose-Uptake and Inhibition of Free Fatty Acids (FFA) -Release in Isolated Rat Adipocytes
• Chemistry and Biochemistry of Insulin-Mimetic Vanadium and Zinc Complexes. Trial for Treatment of Diabetes Mellitus
• An Extremely High Insulin-Mimetic Activity of Bis(1,4-dihydro-2-methyl-1-phenyl-4-thioxo-3-pyridinolato)zinc(II) Complex
• Essential Role of Singlet Oxygen Species in Cytochrome P450-dependent Substrate Oxygenation by Rat Liver Microsomes
• Possible Involvement of Singlet Oxygen Species as Multiple Oxidants in P450 Catalytic Reactions
• Direct Reaction between Shikonin and Thiols Induces Apoptosis in HL60 Cells
• A zinc(II)-glycine complex is an effective inducer of metallothionein and removes oxidative stress
• A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties
• Dysfunction of dermal fibroblasts induced by advanced glycation end-products (AGEs) and the contribution of a nonspecific interaction with cell membrane and AGEs
• POSSIBLE ROLES OF ADVANCED GLYCATION END-PRODUCTS IN PROMOTING SKIN AGING
• Protective Effects of Baicalein against Cell Damage by Reactive Oxygen Species
• Insulinomimetic Zn(II) Complexes as Evaluated by Both Glucose-Uptake Activity and Inhibition of Free Fatty Acids Release in Isolated Rat Adipocytes
• Structure-Activity Relationship of Insulinomimetic Activity of Zinc(II) Complexes with Pyridine-2-sulfonic Acid Derivatives
• In Vitro Alpha-glucosidase Inhibitory Effect of Zn (II) Complex with 6-Methyl-2-picolinmethylamide
• Anti-diabetes Effect of Zn (II)/Carnitine Complex by Oral Administration (Communications to the Editor)
• Quantitative Diagnosis on Magnetic Resonance Images of Chronic Liver Disease Using Neural Networks (Special Section on Nonlinear Theory and Its Applications)
• Differential Reactivity of Metallothionein Isoforms I and II on Active Oxygen Species
• Antioxidative Compounds in the Extracts of Black Rice Brans
• Syntheses, Structures, and Insulin-like Activities of Oxovanadium (IV) Complexes with Tetra-and Penta-dentate Histidine Derivatives
• Peroral cholangioscopy for the diagnosis and treatment of biliary diseases
• Analyses of the Metallothioneins and Trace Metals in the Liver and Serum of the Patients with Hepatocellular Carcinoma
• Measurement of Acoustic Property Distributions of Diseased Heart and Liver Tissues
• Effects of X-ray Irradiation on Genomic DNA Methylation Levels in Mouse Tissues
• New Insulin-Mimetic Zinc(II)Complexes;Bis-maltolato Zinc(II)and Bis-2-hydroxypyridine-N-oxido Zinc(II)with Zn(O_4)Coordination Mode
• Syntheses, Structures, and Insulin-like Activities of Two Vanadyl Complexes;[VO(GeG)(H_2O)]and[VO(MeM)(H_2O)]
• Inhibitory Effects of Alpinia speciosa K. SCHUM on the Porphyrin Photooxidative Reaction
• Local Detection of Aluminum in Livers of Rats Treated with Aluminum-maltolate Complex
• Protective activity of hamamelitannin on cell damage of murine skin fibroblasts induced by UVB irradiation
• Comparative study of insulin-mimetic activity of vanadium and zinc complexes
• Increased generation of hydrogen peroxide possibly from mitochondrial respiratory chain after UVB irradiation of murine fibroblasts
• Superoxide Anion Scavenging Activity and Metal Contents of Coffee
• WHAT KIND OF BENEFIT DO WE EXPECT FOR PERORAL PANCREATOSCOPY IN THE DIAGNOSIS OF INTRADUCTAL PAPILLARY MUCINOUS TUMOR OF THE PANCREAS?
• Aluminum Distribution in Organs of Animals treated with Aluminum Ion and Its Complex
• Suppressive effects of zinc compounds against UVA-induced reactive oxygen species (ROS) in the skin of hairless mice
• Particle Production in de Sitter Spacetime
• The physiological effects of the undercurrent water from Mt. Fuji on type 2 diabetic KK-A^y mice
• Protective effect of metallogluconates against UVA-induced cutaneous lesion in HR-1 hairless mice
• Oral Administration of Bis(aspirinato)zinc(II) Complex Ameliorates Hyperglycemia and Metabolic Syndrome-Like Disorders in Spontaneously Diabetic KK-Ay Mice: Structure–Activity Relationship on Zinc–Salicylate Complexes
• Molecular Mechanism for Antidiabetic Activity of [meso-Tetrakis(4-sulfonatophenyl)porphyrinato]oxovanadium(IV) (VO(tpps)) Complex : Studies on Akt Phosphorylation and GLUT4 Translocation in 3T3-L1 Adipocytes
• Potential Insulinominetic Agents of Zinc(II) Complexes with Picolinamide Derivatives : Preparations of Complexes, in Vitro and in Vivo Studies
• Medicinal Aspects of Vanadium Complexes : Treatment of Diabetes Mellitus in Model Animals
• Specific Binding of Vanadyl Ion (VO^) with Thiolate of the Cysteine-34 Residue in Serum Albumin, Demonstrated by CD Spectroscopy and Kinetic Property
• Evidence for the Improvement of Noninsulin-Dependent Diabetes Mellitus in KKA^y Mice with Daily Oral Administration of Bis(6-methylpicolinato)oxovanadium(IV) Complex
• Inhibitory Effect of Oxovanadium(IV), Copper(II), and Zinc(II) Ions on the Activity of an Alpha-glucosidase from a Saccharomyces sp. (特集1:若手が拓く微量元素研究の最前線)

もっと見る 閉じる

スポンサーリンク