Investigations into Biochemical Changes of Genetic Hypertensive Rats Using ^1H Nuclear Magnetic Resonance-Based Metabonomics
スポンサーリンク
概要
- 論文の詳細を見る
- 2005-05-01
著者
-
Hashimoto T
Faculty Of Pharmaceutical Sciences Hokuriku University
-
橋本 忠
北陸大・薬
-
橋本 忠
北陸大学薬学部
-
AKIRA Kazuki
School of Pharmacy, Tokyo University of Pharmacy and Life Science
-
HASHIMOTO Takao
School of Pharmacy, Tokyo University of Pharmacy and Life Science
-
IMACHI Misako
Bruker BioSpin K. K.
-
Hashimoto Tadashi
Faculty Of Pharmaceutical Sciences Hokuriku University
-
Hashimoto T
Hokuriku Univ. Kanazawa Jpn
-
Akira K
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
-
Akira Kazuki
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
-
Imachi M
Bruker Japan Co. Ltd.
-
Hashimoto Toshihiro
Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ.
-
Hashimoto Tadashi
Drug Metabolism Laboratories Drug Development Division Yamanouchi Pharmaceutical Co. Ltd.
-
Hashimoto Takao
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
関連論文
- Synthesis of Thyrotropin-Releasing Hormone-Related Peptides Using N^α-tert-Bytyloxycarbonyl-ω-(N-tert-butyloxycarbonylcarbamoyl)-α-amino Acids
- Structure-Activity Relationships of Neuromedin U. V. Study on the Stability of Porcine Neuromedin U-8 at the C-Terminal Asparagine Amide under Mild Alkaline and Acidic Conditions
- A3 トロンビンレセプターが介在する血管内皮細胞プロテオグリカン合成の調節
- β-アミロイドペプチド(β25-35)のダンシルラベル体による凝集と蛍光特性変化の解析
- Hydrolytic Cleavage of Pyroglutamyl-Peptide Bond. I. The Susceptibility of Pyroglutamyl-Peptide Bond to Dilute Hydrochloric Acid
- Structure-Activity Relationships of Neuromedin U. II. Highly Potent Analogs Substituted or Modified at the N-Terminus of Neuromedin U-8
- Structure-Activity Relationships of Neuromedin U. I. Contractile Activity of Dog Neuromedin U-Related Peptides on Isolated Chicken Crop Smooth Muscle
- Contractile Activity of Porcine Neuromedin U-25 and Various Neuromedin U-Related Peptide Fragments on Isolated Chicken Crop Smooth Muscle
- Agonistic and Antagonistic Activities of Neuromedin U-8 Analogs Substituted with Glycine or D-Amino Acid on Contractile Activity of Chicken Crop Smooth Muscle Preparations
- Structure-Activity Relationships of Rat Neuromedin U for Smooth Muscle Contraction
- Synthesis of Head Activator (HA)-Related Peptides and Development of HA-Radioimmunoassay(Organic,Chemical)
- PROPERTIES OF N^α, N^-DI- TERT-BUTYLOXYCARBONYL-ω-CARBAMOYL-α-AMINO ACIDS AND DIRECT SYNTHESIS OF PROTECTED HOMOGLUTAMIC ACID DERIVATIVES
- URETHANE TYPE PROTECTING GROUPS FOR CARBOXAMIDE IN PEPTIDE CHEMISTRY
- Active Peptides on Smooth Muscle in the Skin of Bombina orientalis BOULENGER and Characterization of a New Bradykinin Analogue
- Studies on the Synthesis of Proinsulin. I. Synthesis of Partially Protected Tritriacontapeptide related to the Connecting Peptide Fragment of Porcine Proinsulin
- Hydrolytic Cleavage of Pyroglutamyl-peptide Bond. V. Selective Removal of Pyroglutamic Acid from Biologically Active Pyroglutamylpeptides in High Concentrations of Aqueous Methanesulfonic Acid
- Regioselective Hydrolytic Cleavage of N-Terminal Myristoyl-peptide
- Regioselective Hydrolysis of Formyl-peptide in Aqueous Methanesulfonic Acid
- Enzymatic Degradation of Rabbit Neuromedin U-25 Related Peptides
- THE ABSOLUTE STRUCTURES OF NEW 1β-HYDROXY-SACCULATANE-TYPE DITERPENOIDS WITH PISCICIDAL ACTIVITY FROM THE LIVERWORT PELLIA ENDIVIIFOLIA
- Nitric Oxide Synthesis in Murine Peritoneal Macrophages by Fungal β-Glucans
- Synthesis of Neurokinin B Analogs and Their Activities as Agonists and Antagonists(Organic,Chemical)
- Citbismine-A, -B and -C, New Binary Acridone Alkaloids from Citrus Plants
- Highly Selective Hydrolytic Cleavage of Pyroglutamyl-Peptide Bond
- Application of LC-NMR for Characterization of Rat Urinary Metabolites of Zonampanel Monohydrate (YM872)
- 二本立てとその問題点(四年生の講座配属)
- 126(P-68) 抗発ガンプロモーション活性を有するクリプトポール酸の化学(ポスター発表の部)
- LTQ FT MS Accurate Mass and SRM Data Dependent Exclusion MSn Measurements for Structure Determination of FK228 and Its Metabolites (BMS特集号)
- Effect of Nilvadipine, a Dihydropyridine Calcium Antagonist, on Cytochrome P450 Activities in Human Hepatic Microsomes (Biochemistry/Molecular Biology)
- Effect of Cefixime and Cefdinir, Oral Cephalosporins, on Cytochrome P450 Activities in Human Hepatic Microsomes(Biochemistry/Molecular Biology)
- Inhibitory Effects of Amlodipine and Fluvastatin on the Deposition of Advanced Glycation End Products in Aortic Wall of Cholesterol and Fructose-Fed Rabbits(Pharmacology)
- CITBISMINE-A, A NEW BISACRIDONE ALKALOID FROM CITRUS PARADISI
- Inhibitory activity of nitric oxide production in RAW 264.7 cells of daldinals A-C from the fungus Daldinia childiae and other metabolites isolated from inedible mushrooms
- Hydnellins A and B, Nitrogen-Containing Terphenyls from the Mushrooms Hydnellum suaveolens and Hydnellum geogerirum
- Inhibition of Nitric Oxide Production in RAW 264.7 Cells by Azaphilones from Xylariaceous Fungi(Molecular and Cell Biology)
- Pregnane-Type Steroids from the Inedible Mushroom Thelephora terrestris
- Tyromycic Acids F and G: Two New Triterpenoids from the Mushroom Tyromyces fissilis
- Curtisians M-Q: Five Novel p-Terphenyl Derivatives from the Mushroom Paxillus curtisii
- A Novel ent-Kaurane Diterpenoid from the Croton tonkinensis GAGNEP
- Two Novel Ravenelones from the Edible Mushroom Pulveroboletus ravenelii
- STRUCTURES OF DALDINING A〜C, THREE NOVEL AZAPHILONE DERIVATIVES FROM ASCOMYCETOUS FUNGUS KALKINIA CONCENTRICA
- THREE NOVEL POLYACETYLENE TRIGLYCERIDES, LYCOGARIDES A-C, FROM THE MYXOMYCETES LYCOGALA EPIDENDRUM
- STRUCTURES OF A NOVEL BINAPHTHYL AND THREE NOVEL BENZOPHENONE DERIVATIVES WITH PLANT-GROWTH INHIBITORY ACTIVITY FROM THE FUNGUS DALDINIA CONCENTRICA
- STRUCTURES AND TOTAL SYNTHESIS OF TWO NOVEL BIS(BIBENZYLS), PALEATINS A AND B, FROM THE LIVERWORT MARCHANTIA PALEACEA VAR. DIPTERA
- 46 苔類ウスバゼニゴケおよびトサハネゴケより単離された新規大環状ビスビベンジル化合物の構造(口頭発表の部)
- 61 真性粘菌マメホコリの新規ポリアセチレントリグリセリドおよびインドロカルバゾール系化合物の構造(ポスター発表の部)
- 11 変形菌類マメホコリの新規ポリアセチレントリグリセライドおよびジベンゾカルバゾール誘導体の構造(口頭発表の部)
- サルノコシカケ科ヒトクチタケの苦味セスキテルペノイド
- Tetrapetalone A, a Novel Lipoxygense Inhibitor from Streptomyces sp.
- Regioselective Cleavage of Myristoyl-Peptide in Acidic Solution
- Development of Neuromedin U Agonist with Specifically Potent Contractile Activity on Rat Uterus Smooth Muscle
- 68(P-55) アブラムシに含まれる色素の研究(ポスター発表の部)
- Isolation, Synthesis and Biological Activity of Grifolic Acid Derivatives from the Inedible Mushroom Albatrellus dispansus
- [1-^C]Octanoate as a PET Tracer for Studying Ischemic Stroke : Evaluation in a Canine Model of Thromboembolic Stroke with Positron Emission Tomography
- Degradation of the C-Terminal Asparagine Amide in Neuromedin U-8
- 67(P43) ウスバゼニゴケ科苔類から得られるフェノール性化合物(ポスター発表の部)
- P-24 5種の子嚢菌類に含まれる新規Cytochalasin類、Azaphilone類および芳香族化合物の構造(ポスター発表の部)
- Effect of β-Glucans on the Nitric Oxide Synthesis by Peritoneal Macrophage in Mice
- Studies on Cardiac Ingredients of Plants. XIII : Chemical Modification of Gitoxin to Cardiotonic Compounds without Vascular Contractile Effect
- AN UNUSUAL FLUORIDE-MEDIATED OXIDATION OF GITOXIN
- Determination of D- and L-enantiomers of methionine and [^2H_3]methionine in plasma by gas chromatography-mass spectrometry
- Simultaneous determination of methionine and total homocysteine in human plasma by gas chromatography-mass spectrometry
- Kinetics of Intramolecular Acyl Migration of 1β-O-Acyl Glucuronides of(R)-and(S)-2-Phenylpropionic Acids
- Gas chromatographic-mass spectrometric determination of α-ketoisocaproic acid and [^2H_7] α-ketoisocaproic acid in plasma after derivatization with N-phenyl-1, 2-phenylenediamine
- Stereoselective Internal Acyl Migration of 1β-O-Acyl Glucuronides of Enantiomeric 2-Phenylpropionic Acids
- Preliminary evaluation of [1-^C]octanoate as a PET tracer for studying cerebral ischemia: A PET study in rat and canine models of focal cerebral ischemia
- Biotransformation of hinesol Isolated from the Crude Drug Atractylodes Iancea by Aspergillus niger and Aspergillus cellulosae
- Structures of Four Novel Highly Oxygenated Labdane-Type Diterpenoids, Ptychantins F-I, from the Liverwort Ptychanthus striatus
- The Structures of Claudimerines-A and -B, Novel Bicoumarins from Citrus hassaku
- Hydrolytic Cleavage of Pyroglutamyl-Peptide Bond. II. Effects of Amino Acid Residue Neighboring the pGlu Moiety
- HIGHLY SELECTIVE CLEAVAGE OF PYROGLUTAMYL-PEPTIDE BOND IN CONCENTRATED HYDROCHLORIC ACID
- Decomposition of pyroglutamyl-Peptides in Dilute Acid
- 66 苔類コハネゴケに含まれる新規フシコカン型ジテルペノイドの単離と構造
- 17 キラル異方性試薬による直鎖状アルコールおよびカルボン酸の絶対配置およびコンホメーション解析(口頭発表の部)
- Isolation and Structures of New Cyclomyltaylane and ent-Chamigrane-Type Sesquiterpenoids from the Liverwort Reboulia hemishaerica and Their Biotransformation by the Fungus Aspergillus niger
- Biotransformation of Aristolane- and 2,3-Secoaromadendrane-Type Sesquiterpenoids Having a 1,1-Dimethylcyclopropane Ring by Chlorella fusca var. vacuolata, Mucor Species, and Aspergillus niger
- Highly Efficient Production of Nootkatone, the Grapefruit Aroma from Valencene, by Biotransformation(Communications to the Editor)
- Biotransformation of Citrus Aromatics Nootkatone and Valencene by Microorganisms
- Investigations into Biochemical Changes of Genetic Hypertensive Rats Using ^1H Nuclear Magnetic Resonance-Based Metabonomics
- Hydrolytic Cleavage of Pyroglutamyl-Peptide Bond. IV. Highly Selective Cleavage of Thyrotropin Releasing Hormone (TRH) in Aqueous Methanesulfonic Acid
- Structure-Activity Relationships of Neuromedin U.IV. Absolute Requirement of the Arginine Residue at Position 7 of Dog Neuromedin U-8 for Contractile Activity
- Determination of the Absolute Configuration of Ginnol, a Long-chain Aliphatic Alcohol, by Use of a New Chiral Anisotropic Reagent
- Use of ^C Labeling and NMR Spectroscopy for the Investigation of Degradation Pathways of Amadori Compounds(Analytical Biochemistry)
- Analysis of [^2H_7]methionine, [^2H_4]methionine, methionine, [^2H_4]homocysteine and homocysteine in plasma by gas chromatography-mass spectrometry to follow the fate of administered [^2H_7]methionine
- Isoplagiochins C and D, New Type of Macrocyclic Bis(bibenzyls), Having Two Biphenyl Linkages from the Liverwort Plagiochila fruticosa
- PA33 CRYPTOPORIC ACIDS C, D, E, F, AND G, NOVEL BITTER DRIMANE SESQUITERPENOID ETHERS, FROM THE FUNGUS CRYPTOPORUS VOLVATUS
- Biotransformation of Terpenoids from the Crude Drugs and Animal Origin by Microorganisms
- Hydrolytic Cleavage of Pyroglutamyl-peptide Bond. III. A Highly Selective Cleavage in 70% methanesulfonic Acid
- Tissue Selective Contractile Activity of Neuromedin U Analogs on Isolated Smooth Muscles
- Structure-Activity Relationships of Neuromedin U. III. Contribution of Two Phenylalanine Residues in Dog Neuromedin U-8 to the Contractile Activity
- Structure-Activity Relationships of Hydrophobic Region of Neuromedin U-8 Peptide
- 86(PA3-6) 苔類コハネゴケの新規大環状ビスビベンジルの構造(ポスター発表の部)
- FIVE NEW DIARYLHEPTANOIDS FROM THE MALE FLOWERS OF ALNUS SIEBOLDIANA
- A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on ^1H NMR spectroscopic urinalysis
- Identification of Enzymes Responsible for the N-Oxidation of Darexaban Glucuronide, the Pharmacologically Active Metabolite of Darexaban, and the Glucuronidation of Darexaban N-Oxides in Human Liver Microsomes