Interconversion of the Product Specificity of Type I Eubacterial Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase through One Amino Acid Substitution

スポンサーリンク

概要

• 論文の詳細を見る
• Japanese Biochemical Societyの論文
• 2003-01-01

著者

• SETO Haruo

  Faculty of Applied Biosciences, Tokyo University of Agriculture

• Itoh N

  Biotechnology Research Center Toyama Prefectural University

• Itoh Nobuya

  Biotechnology Research Center Toyama Prefectural University

• KUZUYAMA Tomohisa

  Institute of Molecular and Cellular Biosciences, University of Tokyo

• DAIRI Tohru

  Biotechnology Research Center, Faculty of Engineering, Toyama Prefectural University

• KAWASAKI TAKASHI

  Biotechnology Research Center, Toyama Prefectural University

• Kawasaki Takashi

  Biotechnology Research Center Toyama Prefectural University

• Yamashita H

  Biotechnology Research Center Toyama Prefectural University

• Seto H

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Hamano Yoshimitsu

  Biotechnology Research Center Toyama Prefectural University

• Dairi T

  Biotechnology Res. Center Toyama Prefectural Univ.

• Dairi Tohru

  Biotechnology Research Center Toyama Prefectrual University

• Kunigami T

  Biotechnology Research Center Toyama Prefectural University

• Seto H

  Faculty Of Applied Bioscience Tokyo University Of Agriculture

• Seto Haruo

  Department Of Applied Biology And Chemistry Tokyo University Of Agriculture

• Kuzuyama T

  Univ. Tokyo Tokyo

• Kuzuyama Tomohisa

  Biotech. Research Center Tokyo Univ.

• Kuzuyama Tomohisa

  Institute Of Molecular And Cellular Biosciences The University Of Tokyo

• Dairi Tohru

  Hokkaido Univ. Hokkaido Jpn

• Seto Haruo

  Faculty of Applied Bio-science, Tokyo University of Agriculture

関連論文

• Burkholone, A New Cytotoxic Antibiotic against IGF-I Dependent Cells from Burkholderia sp.
• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. II. Structure Elucidation
• Oximidine III, a New Antitumor Antibiotic against Transformed Cells from Pseudomonas sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from Excitotoxicity : II. Structure Determination
• Structure of Thioviridamide, a Novel Apoptosis Inducer from Streptomyces olivoviridis
• Thioviridamide, a Novel Apoptosis Inducer in Transformed Cells from Streptomyces olivoviridis
• Studies on Terpenoids Produced by Actinomycetes : Isolation and Structural Elucidation of Antioxidative Agents, Naphterpins B and C
• Structure of Tyroscherin, an Antitumor Antibiotic against IGF-1-dependent Cells from Pseudallescheria sp
• Structure of Aspochalasin H, a New Member of the Aspochalasin Family
• A Novel Neuronal Cell Protecting Substance, Halxazone, Produced by Streptomyces halstedii
• Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neuronal Cells from Excitotoxicity : I. Fermentation, Isolation, Physico-chemical Properties and Biological Activity
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : II. Physico-chemical Properties and Structure Elucidation
• Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. : I. Production, Isolation and Biological Activity
• Selective Cytotoxicity and Stereochemistry of Aspochalasin D
• Phoenistatin, A New Gene Expression-Enhancing Substance Produced by Acremonium fusigerum
• Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp.
• Bacillus subtilis ypgA Gene Is fni, a Nonessential Gene Encoding Type 2 Isopentenyl Diphosphate Isomerase
• Diheteropeptin, a Novel Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : II. Physico-chemical Properties and Structure Elucidation
• Diheteropeptin, a New Substance with TGF-β-like Activity, Produced by a Fungus, Diheterospora chlamydosporia : I. Production, Isolation and Biological Activities
• Studies on the Biosynthesis of Terpenoid Compounds Produced by Actinomycetes 3. Biosynthesis of the Isoprenoid Side Chain of Novobiocin via the Non-mevalonate Pathaway in Streptomyces niveus
• Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp.
• Cytovaricin B, a New Inhibitor of JAK-STAT Signal Transduction Produced by Streptomyces torulosus
• Thermostabilization of Ovotransferrin by Anions for Pasteurization of Liquid Egg White
• Structural Characteristics of the Disulfide-reduced Ovotransferrin N-Lobe Analyzed by Protein Fragmentation
• Nucleotide Sequences of Genes Encoding Allosamidin-sensitive and -insensitive Chitinases Produced by Allosamidin-producing Streptomyces(Biochemistry & Molecular Biology)
• Cloning and Expression in Escherichia coli of 2-Hydroxypropylphosphonic Acid Epoxidase from the Fosfomycin-producing Organism, Pseudomonas syringae PB-5123
• Nucleotide Sequence of Fortimicin KL1 Methyltransferase Gene Isolated from Micromonospora olivasterospora, and Comparison of Its Deduced Amino Acid Sequence with Those of Methyltransferases Involved in the Biosynthesis of Bialaphos and Fosfomycin
• Effects of Hibarimicins and Hibarimicin-Related Compounds Produced by Microbispora on v-Src Kinase Activity and Growth and Differentiation of Human Myeloid Leukemia HL-60 Cells
• Cloning of the Gene Cluster Responsible for the Biosynthesis of Brasilicardin A, a Unique Diterpenoid
• Presence of Copalyl Diphosphate Synthase Gene in an Actinomycete Possessing the Mevalonate Pathway
• Studies on Terpenoids Produced by Actinomycetes : 5-Dimethylallylindole-3-carboxylic Acid and A80915G-8"-acid Produced by Marine-derived Streptomyces sp. MS239
• P-355 Biosynthesis of a Natural Polyketide-Isoprenoid Hybrid Compound Furaquinocin A : Identification and Heterologous Expression of the Gene Cluster
• P-238 Studies on terpenoids produced by Actinomycetes
• Trichostatin D, a New Inducer of Phenotypic Reversion in Transformed Cells
• Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus
• Detection of the Mevalonate Pathway in Streptomyces Species by Utilization of the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene
• Carquinostatin B, a New Neuronal Cell-protecting Substance Produced by Streptomyces exfoliatus
• Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Biodies of Fistulina hepatica
• New Ravidomycin Analogues, FE35A and FE35B, Apotosis Inducers Produced by Streptomyces rochei
• A Novel Neuronal Cell Protecting Substance, Aestivophoenin C, Produced by Streptomyces purpeofuscus
• A Novel Substance with TGF-β like Activity, Diheteropeptin, Produced by a Fungus, Diheterospora sp.
• Isolation and Structure Elucidation of Novel Neuronal Cell Protecting Substances, Carazomadurins A and B Produced by Actinomadura madurae
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D II. Physicochemical Properties and Structure Elucidation
• Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D I. Taxonomy, Fermentation, Isolation and Biological Activities
• Limited Proteolysis of Disulfide-reduced Ovalbumin by Subtilisin
• Functional Analysis of Eubacterial ent-Copalyl Diphosphate Synthase and Pimara-9(11),15-Diene Synthase with Unique Primary Sequences
• Cloning of the Gene Cluster Responsible for Biosynthesis of KS-505a (Longestin), a Unique Tetraterpenoid
• A Self-defense Gene Homologous to Tetracycline Effluxing Gene Essential for Antibiotic Production in Streptomyces aureofaciens
• Conserved Organization of Genes for Biosynthesis of Chlortetracycline in Streptomyces Strains
• Cloning and Nucleotide Sequence of the Gene Responsible for Chlorination of Tetracycline
• A Relationship between the Mevalonate Pathway and Isoprenoid Production in Actinomycetes
• Comparison of the Enzymatic Properties of ent-Copalyl Diphosphate Synthases in the Biosynthesis of Phytoalexins and Gibberellins in Rice
• Identification of Diterpene Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases in Phomopsis amygdali
• A Neuronal Cell Protecting Substance, 4-Demethoxymicigazone, produced by Streptomyces halstedii
• Shotgun Cloning and Characterization of the Thymidylate Synthase-Encoding Gene from Mycobacterium bovis BCG
• Gene Cloning and Expression of Leifsonia Alcohol Dehydrogenase (LSADH) Involved in Asymmetric Hydrogen-Transfer Bioreduction to Produce (R)-Form Chiral Alcohols
• Novel Neuronal Cell Protecting Substances, Aestivophoenins A and B, Produced by Streptomyces purpeofuscus
• A New Neuronal Cell Protecting Substance, Lavanduquinocin, Produced by Streptomyces viridochromogenes
• Identification and Cloning of the Gene Involved in the Final Step of Chlortetracycline Biosynthesis in Streptomyces aureofaciens
• Detection of the Mevalonate Pathway in Streptomyces Species Using the 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene
• Purification and Characterization of a Monohalomethane-producing Enzyme S-adenosyl-L-methionine : Halide Ion Methyltransferase from a Marine Microalga, Pavlova pinguis(Biochemistry & Molecular Biology)
• Efficient Transformation of Pseudomonas Strains with pNI Vectors by Electroporation
• Thiopeptide Non-producing Streptomyces Species Carry the tipA Gene : A Clue to Its Function
• Comparison of Two C-P Bond-forming Enzymes Involved in the Biosynthesis of Bialaphos(Biological Chemistry)
• Major Anthocyanin of the Flowers of Hibiscus (Hibiscus rosa-sinensis L.)(Organic Chemistry)
• Heterologous Mevalonate Production in Streptomyces lividans TK23
• Interconversion of the Product Specificity of Type I Eubacterial Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase through One Amino Acid Substitution
• Growth-phase Dependent Expression of the Mevalonate Pathway in a Terpenoid Antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• Cloning of a Gene Cluster Encoding Enzymes Responsible for the Mevalonate Pathway from a Terpenoid-antibiotic-producing Streptomyces Strain(Microbiology & Fermentation Technology)
• Cloning and Nucleotide Sequence of the Putative Polyketide Synthase Genes for Pradimicin Biosynthesis from Actinomadura hibisca
• Protoplasting and Regeneration of Strains Belonging to the Genus Actinomadura
• Nucleotide Sequencing of Phenylalanine Dehydrogenase Gene from Bacillus badius IAM 11059
• Identification of Diterpene. Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases in Phomopsis amygdali
• Comparison of the Enzymatic Properties of ent-Copalyl Diphosphate Synthases in the Biosynthesis of Phytoalexins and Gibberellins in Rice
• Crystal Structure of 1-Deoxy-D-xylulose 5-phosphate Reductoisomerase Complexed with Cofactors : Implications of a Flexible Loop Movement upon Substrate Binding
• Construction and Characterization of Escherichia coli Disruptants Defective in the yaeM Gene
• Cloning of the Gene Cluster Responsible for Biosynthesis of KS-505a (Longestin), a Unique Tetraterpenoid
• Enzymatic Properties of Futalosine Hydrolase, an Enzyme Essential to a Newly Identified Menaquinone Biosynthetic Pathway
• 1P058 Development and evaluation of a system for scoring the local structural segment configuration(1. Protein structure and dynamics (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
• Studies on Antibiotic-Biosynthetic Genes and Enzymes Catalyzing Unique Reactions
• Studies on Biosynthetic Genes and Enzymes of Isoprenoids Produced by Actinomycetes
• Anguinomycins C and D, New Antitumor Antibiotics with Selective Cytotoxicity against Transformed Cells
• Studies on the Biosynthesis of Bialaphos. Biochemical Mechanism of C-P Bond Formation: Discovery of Phosphonopyruvate Decarboxylase which Catalyzes the Formation of Phosphonoacetaldehyde from Phosphonopyruvate
• Biochemical Mechanism of C-P Bond Formation of Bialaphos : Use of Gene Manipulation for the Analysis of the C-P Bond Formation Step(Biological Chemistry)
• Purification and Characterization of Citrate Synthase from Streptomyces hygroscopicus SF-1293 and Comparison of Its Properties with Those of 2-Phosphinomethylmalic Acid Synthase(Biological Chemistry)
• Trachyspic Acid, a New Metabolite Produced by Talaromyces trachyspermus, that Inhibits Tumor Cell Heparanase:Taxonomy of the Producing Strain, Fermentation, Isolation, Structural Elucidation, and Biological Activity
• Selective Cytotoxicity of Mycophenolic Acid against Transformed Cells
• Genetic Transformation in a Synchronous Culture of Streptococcus pneumoniae(Microbiology & Fermentation Industry)
• Site-directed Mutagenesis of Two Zinc-binding Centers of the NADH-dependent Phenylacetaldehyde Reductase from Styrene-assimilating Corynebacterium sp. Strain ST-10
• Actions of Pokeweed Antiviral Protein on Virus-infected Protoplasts
• Characterization of Styrene Oxide Isomerase, a Key Enzyme of Styrene and Styrene Oxide Metabolism in Corynebacterium sp.
• Fosfomycin Monophosphate and Fosfomycin Diphosphate, Two inactivated Fosfomycin Derivatives Formed by Gene Products of fomA and fomB from a Fosfomycin Producing Organism Streptomyces wedmorensis
• Fosfomycin Biosynthesis and Self-Resistance Mechanism of the Producing Organism Streptomyces wedmorensis
• Molecular Breeding of a Fungus Producing a Precursor Diterpene Suitable for Semi-Synthesis by Dissection of the Biosynthetic Machinery
• Ammocidins B, C and D, new cytotoxic 20-membered macrolides from Saccharothrix sp. AJ9571
• Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II
• Branched fatty acids inhibit the biosynthesis of menaquinone in Helicobacter pylori
• Isolation and structure elucidation of tumescenamides A and B, two peptides produced by Streptomyces tumescens YM23-260
• Terpenoids produced by actinomycetes : isolation, structural elucidation and biosynthesis of new diterpenes, gifhornenolones A and B from Verrucosispora gifhornensis YM28-088
• An alternative menaquinone biosynthetic pathway operating in microorganisms : an attractive target for drug discovery to pathogenic Helicobacter and Chlamydia strains

もっと見る 閉じる

スポンサーリンク