Studies of Peptide Antibiotics. XXIV. Synthesis of 4,4′-D-Alanine-gramicidin S
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概要
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In order to investigate the contribution to antibacterial activity of the D-phenylalanine residues at 4- and 4′-position in gramicidin S, 4,4′-D-alanine-gramicidin S (XX) and 4-D-alanine-semigramicidin S (XXI) were prepared and tested for antibacterial properties. XX exhibited recognizable activity though weaker than that of gramicidin S, whereas XXI showed no activity on any of the microorganisms tested.
- 公益社団法人 日本化学会の論文
著者
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Lee Sannamu
Laboratory Of Biochemistry Faculty Of Science Kyushu University
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Izumiya Nobuo
Laboratory Of Biochemistry Faculty Of Engineering Kyushu Sangyo University
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Ohkawa Reiko
Laboratory of Biochemistry, Faculty of Science, Kyushu University
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