Experimental study of the physical properties of the cupula. Effect of cupula sectioning on the ampullary nerve action potential.:Effect of Cupula Sectioning on the Ampullary Nerve Action Potential

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A bullfrog's posterior semicircular canal (p. s. c.) was isolated, and the ampullary wall was cut and the cupula removed with glass micropipettes. The cupula was replaced on the crista, and the p. s. c. ampullary action potential was recorded. The cupula was again removed and cut in half either in the plane vertical to the crista (vertical sectioning) or in the plane parallel to the crista (horizontal sectioning). Then, the sectioned half of the cupula was replaced on the crista. The action potentials after replacement of vertical or horizontal half were compared with those when the entire Cupula was replaced. After vertical sectioning, the action potentials were markedly reduced to 50.3% of the replaced entire cupula for weak stimuli, and 79.1% for strong stimuli. Reduction of the attachment surface between the cupula base and the crista may be responsible for the decreased action potential after vertical sectioning. After horizontal sectioning, the action potentials were 64.5% for weak stimuli and 108.2% for strong stimuli. These results indicate that the responses are related to the cupula height and the deflection angle. This further suggests that the movement of the cupula can be represented by that of an elastic system.
耳鼻咽喉科臨床学会の論文