ストレプトマイシン投与患者の平衡機能検査所見 (前庭機能異常の研究-3-<特集>)

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Vestibular function tests were performed in 42 patients who had received streptomycin (SM) injections. The results of the vestibular function tests were analyzed together with symptoms, results of audiometry and SM dosage.Mann's test was positive in only 28.6% of the patients, although the one-leg standing test and stepping test yielded 61.9% and 54.8% positive rates, respectively. Since all the patients with abnormal Mann's test also showed poor results in the standing test, the standing test should be given top priority for screening vestibular dysfunction. In Mann's test, the average dosage of SM in the positive patients tended to be greater than that of the negative patients, whereas in both standing and stepping tests, the averaged SM dosage were not different among the positive and negative patients. Among the parameters of the stepping test, abnormal values were far more frequently found in the distance of shift, rather than the angle of rotation. This may indicate a low chance of unilateral damage to the vestibular system in SM patients.Spontaneous nystagmus was observed in 11.9% of the total patients.The caloric test revealed either CP or DP in 7 patients (18.5%). All of these patients showed almost the same hearing threshold bilaterally, indicating that the laterality of the vestibular function was not related to the threshold of hearing.The averaged audiometry thresholds were 11.5dB in the middle and low frequency range and 37.7dB at 8kHz. The thresholds of hearing were not parallel to the average dosage of SM.
耳鼻咽喉科臨床学会の論文

ストレプトマイシン投与患者の平衡機能検査所見 (前庭機能異常の研究-3-<特集>)

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