半規管クプラの実験的研究--クプラへの直接刺激法について

概要

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The ampullary wall of the isolated frog posterior semicircular canal was cut, and the cupula was exposed in frog Ringer's solution. The cupula was stimulated by depressing it with a fine glass micropipette at three points: A, the lowest point on the midline of the cupula surface of the utricular side, B, the uppermost point on the midline of the same surface, and C, in the middle of the lateral surface of the cupula. The direction of depression at points A and B was towards the canal, whereas depression at point C was towards the center of the cupula. The amount of depression was controlled by a micromanipulator. At point A, the minimum depression which facilitated the posterior canal action potential was 1μm. At point B, more depression was needed to produce the action potential. Depression at point C caused only a small action potential, even with a large amount of depression, possibly because sensory cell polarity is on the long axis of the canal.
耳鼻咽喉科臨床学会の論文