上咽頭癌の臨床的観察:-当科15年間の集計-

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We reviewed 36 consecutive patients with epipharyngeal carcinoma treated at our hospital between 1978 and 1993.<BR>The overall 5-year survival rate was 51.3% (Kaplan-Meier method). The effect of chemotherapy with cisplatinum (CDDP) or its analog (CBDCA) on the long term results of these cases was investigated. Since 1986, we have administered chemotherapy consisting of CDDP (80 mg/m2 intravenous injection on day 1) or CBDCA (400 mg/m2 intravenous injection on day 1) and peplomycin (5 mg/body intramuscular injection on day 2-6) or 5-FU (1000 mg/body intravenous injection on day 2-6).<BR>During the initial treatment, these drugs did not contribute to the survival rate. However, in recurrent cases, these drugs did contribute to the survival rate; the 5-year survival rate was 50.0% in the group treated with chemotherapy including CDDP or CBDCA,9.0% in the group treated with another.
耳鼻咽喉科臨床学会の論文