Age-related Changes of .ALPHA.-Tocopherol Transfer Protein Expression in Rat Liver.
スポンサーリンク
概要
- 論文の詳細を見る
Developmental changes in expression of α-tocopherol transfer protein (α-TTP) after birth were investigated using rats with respect to plasma changes of tocopherols. The expression of α-TTP in the neonatal rat liver, which was very low immediately after birth, increased steadily during the two weeks of life before weanling and reached the adult level at four weeks. During the suckling period, the plasma ratio of α-tocopherol to γ-tocopherol linearly increased, because plasma α-tocopherol which was low immediately after birth, increased rapidly during the period, while γ-tocopherol remained unchanged. The increase in the ratio seemed to correlate with the developmental expression of α-TTP in the liver during this period. The ratio also reached the adult level after four weeks. The expression of α-TTP was investigated using primary cultured rat hepatocytes. The expression of α-TTP was found to be extremely low after 20h of culture. The decrease in a-TTP expression was exacerbated by adding epidermal growth factor to the culture medium and was inhibited by adding dexamethasone. These observations suggest that expression of α-TTP may be affected by the state of hepatic differentiation.
- 財団法人 学会誌刊行センターの論文
著者
-
Tamai Hiroshi
Department Of Fusion Plasma Research Japan Atomic Energy Research Institute
-
Ogihara Tohru
Department Of Internal Medicine Hiratsuka City Hospital
-
Mino Makoto
Department Of Pediatrics Osaka Medical College
-
Inoue Keizo
Department Of Biochemistry And Molecular Biology Indiana University
-
Kim Han-suk
Department Of Pediatrics Osaka Medical College
-
Arita Makoto
Department Of Cardiology Yufuin Kohseinenkin Hospital
-
Sato Yuji
Department Of Bacteriology National Institute Of Health
-
Arai Hiroyuki
Department Of Applied Chemistry Tokai University
-
INOUE Keizo
Department of Health Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokyo
-
OGIHARA Tohru
Department of Pediatrics, Osaka Medical College
-
ARITA Makoto
Department of Health Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokyo
-
ARAI Hiroyuki
Department of Health Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokyo
関連論文
- EPR,^F-ENDOR and^Mn-ENDOR of Mn^ Impurity Center in MgF_2 Single Crystal
- Functional analysis of PTPN11/SHP-2 mutants identified in Noonan syndrome and childhood leukemia
- Impurity Behavior during the H-Mode in JFT-2M
- Ion Bernstein Wave Experiment on JFT-2M Tokamak
- Enhancement of Wall Fueling and Improvement in nτ of a Beam-Heated H-Mode Discharge by Electron Cyclotron Wave in the JFT-2M Tokamak
- Measurement of Peripheral Electron Temperature by Electron Cyclotron Emission during the H-Mode Transition in JFT-2M Tokamak
- Involvement of Vascular Angiotensin II-Forming Enzymes in the Progression of Aortic Abdominal Aneurysms in Angiotensin II-Infused ApoE-Deficient Mice
- Enhanced Degradation of Phospholipids by Phospholipase A2 in Liver of Carbon Tetrachloride-Treated Rat
- OJ-199 Role of Chymase and MMPs in Angiotensin II-induced Abdominal Aortic Aneurysms(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- The Effects of Chymase on Matrix Metalloproteinase-2 Activation in Neointimal Hyperplasia after Balloon Injury in Dogs
- SUPPRESSION OF VENTRICULAR PREMATURE CONTRACTIONS CONTINUES AFTER THE WASHOUT OF ANTIARRHYTHMIC DRUGS
- EPR Study of Monoclinic Centres in CsCdF_3 and CsCaF_3 Co-Doped with Gd^ and Na^+ Ions
- EPR Study of Tetragonal and Orthorhombic Fe^ Centres in Rb_2CdF_4 Crystals
- Evidence of Structural Phase Transition in K_2CdF_4 Derived from EPR Measurements for Cr^ Centres
- Host Lattice Effects in the EPR Spectra of Cr^-Li^+ and Cr^-V_ Centres in A_2MgF_4 (A=K,Rb) Crystals
- Electron Paramagnetic Resonance of Gd^ Centres in Rb_2CdF_4 and Cs_2CdF_4 Crystals
- EPR Study of Fe^-V_and Fe^-Li^+Centres in RbCdF_3 and CsCdF_3 Crystals
- Three brothers of X-linked agammaglobulinemia : the relation between phenotype and neutropenia
- Effects of Protium Introduction on Electrical and Optical Properties of Tin-Germanium Oxide Thin Films
- Effects of Hydrogen Introduction on Electrical and Optical Properties of Cd-doped Ge Oxide and Zn Oxide Thin Films
- Criteria for medical intervention in obese children : A new definition of 'Obesity disease' in Japanese children
- Induction of Apoptosis by Phosphatidylserine
- 4 Recovery Phase Admission Type Cardic Rehabilitation Program. Importance of the Network System with Acute Phase and Recovery Phase Rehabilitation Facilities(Cardiac Rehabilitation Therapy at the Chronic Stage, The 71st Annual Scientific Meeting of the Ja
- An ACTH-Producing Pituitary Carcinoma Developing Cushing's Disease
- A study of bone mineral density and physical growth in very low birth-weight infants after their discharge from hospital
- Bone status assessment in preterm and term infants by dual-energy X-ray absorptiometry
- Electrical and Optical Properties of Germanium-Doped Zinc Oxide Thin Films
- Spin-Hamiltonian separation and proper coordinate system for orthorhombic EPR spectra of 3d3 ions
- Fine structure interaction of 3d3 ions in ionic crystals
- Thermal Anomalies in Bi_2WO_6 and EPR of Doped Gd^ Ions
- Spin Hamiltonian for a pair of magnetic ions
- Calculation of anisotropic g tensor for a trigonal Cr3+ centre in KZnF3 by ligand-distortion model
- EPR Study of Local Position for Fe^ in Layer Oxide Bi_2WO_6
- Membrane Structure of the Hepatitis B Virus Surface Antigen Particle
- A Monoclonal Antibody, 3A10, Recognizes a Specific Amino Acid Sequence Present on a Series of Developmentally Expressed Brain Proteins
- Localization of the Phosphatidylserine-Binding Site of Glyceraldehyde-3-Phosphate Dehydrogenase Responsible for Membrane Fusion
- Specific Binding of a Synthetic Peptide Derived from an Antibody Complementarity Detemining Region to Phosphatidylserine
- Study of Runaway Electron Transport in Edge Stochastic Magnetic Field in the JFT-2M Tokamak
- FACTORS RESPONSIBLE FOR LOW RESTING MEMBRANE POTENTIALS IN HUMAN ATRIAL MYOCARDIUM : Electrophysiology(I) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- MECHANISM OF ISOPROTERENOL-INDUCED INHIBITION OF RESIDUAL FAST CHANNEL IN VENTRICULAR MUSCLE : A POSSIBLE ROLE OF β-ADRENOCEPTORS : Electrophysiology(I) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- Automaticity and Time-Dependent Conduction Disturbance Produced in Canine Ventricular Myocardium New Aspects for Initiation of Ventricular Arrhythmias : Symposium on Electrophysiological Basis for the Genesis and the Treatment of Arrhythmias
- Lysophosphatidylserine Enhances Exogenous Type II Phospholipase A_2-Induced Activation of Rat Serosal Mast Cells
- Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones
- Metal Cation-Exchanged Montmorillonite (M^-Mont)-Catalyzed Friedel-Crafts Acylation of 1-Methyl-1-cyclohexene and 1-Trimethylsilyl-1-alkynes
- Method of ranking of heart valve characteristics at mitral position based on statistical model analysis
- Pharmacokinetics of All-trans Retinoic Acid in Pediatric Patients with Leukemia
- Psychosocial factors affecting psychosomatic symptoms in Japanese schoolchildren
- CUMULATIVE EFFECTS OF HEART BEAT ON VENTRICULAR PREMATURE CONTRACTIONS SUGGESTING POSSIBLE INVOLVEMENT OF TRIGGERED ACTIVITY
- HEART RATE-DEPENDENT ALTERATION OF THE FREQUENCY AND COUPLING INTERVAL OF VENTRICULAR ARRHYTHMIAS AS MEASURED BY 24-HOUR ECG MONITORING
- -120-THE CHANGE OF VENTRICULAR PREMATURE CONTRACTIONS AFTER ANTIARRHYTHMIC DRUG DISCONTINUATION : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- INTERACTION OF SAPONINS WITH RED BLOOD CELLS AS WELL AS WITH THE PHOSPHATIDYLCHOLINE LIPOSOMAL MEMBRANES
- Febrile seizures associated with influenza A
- Pharmacokinetics of Low-Dose All-trans Retinoic Acid in Japanese Children with Cancer
- Prolonged left homonymous hemianopsia associated with migraine-like attacks in a child with Sturge-Weber syndrome
- Children's toxicology from bench to bed - Liver Injury (2) : Mechanism of antioxidant therapy for nonalcoholic fatty liver disease
- Measurement of Retinoids and β-Carotene 15, 15'-Dioxygenase Activity in HR-1 Hairless Mouse Skin with UV Exposure
- White matter lesion due to dural sinus thrombosis in an infant with subdural hematoma
- Altered Expression of Both β-Carotene 15,15'Monooxygenase and Lecithin : Retinol Acyltransferase in Obese Zucker Rats
- Two Cases in which an Abnormal Hemoglobin (Hb Kamakura) was Identified on the Basis of an Abnormally Low Glycohemoglobin Levels
- Evaluation of joint laxity against distal traction force upon flexion in cruciate-retaining and posterior-stabilized total knee arthroplasty
- 重症仮死児に対する硫酸マグネシウムの効果に関する無作為比較対照試験
- Oseltamivir treatment for children showing abnormal behavior during influenza virus infection
- Neopterin, biopterin, and nitric oxide concentrations in the cerebrospinal fluid of children with central nervous system infections
- Clinical Research : Cerebrospinal Fluid and Serum Neuron-Specific Enolase Levels After Febrile Seizures
- Neurodevelopmental outcome of infants with birth asphyxia treated with magnesium sulfate
- The Safety of High-Dose Vitamin E Supplementation in Healthy Japanese Male Adults
- MEVALONIC ACIDEMIA : FIRST CASE OF JAPAN
- Direct Matrix Diagonalization of Spin Hamiltonian for Cr^ Pair Centre in CsMgCl_3
- 超低出生体重児における難治性低血圧に対する低容量バゾプレッシン投与について
- Kawasaki Disease in a Patient with Wiskott-Aldrich Syndrome : An Increase in the Platelet Count
- THE METABOLISM OF PLATELET ACTIVATING FACTOR IN PLATELETS AND PLASMA OF VARIOUS ANIMALS
- 感染によると思われる関節炎4症例の検討
- Investigation of Insulin Sensitivity in Children of Different Ages by Glucose, Insulin, and Somatostatin Infusion
- Dual Pathways for the Secretion of Lysosomal Cholesterol into a Medium from Cultured Macrophages
- Plasma β-Carotene, Retinol, and α-Tocopherol Levels in Relation to Glycemic Control of Children with Insulin-Dependent Diabetes Mellitus
- Effects of sequential and discrete rapid naming on reading in Japanese children with reading difficulty
- Comparison of bioelectrical impedance analysis and dual energy X-ray absorptiometry for assessment of body composition in children
- Risk factors for the development of Escherichia coli O157:H7 associated with hemolytic uremic syndrome
- Iopamidol enema treatment for meconium obstruction of prematurity in extremely low-birth weight infants : a safe and effective method
- β-Carotene 15,15'-Dioxigenase Activity in Streptozotocin-Induced Diabetic Rats
- Resolution of Cranial MRI and SPECT Abnormalities in a Patient with Wilson's Disease Following Oral Zinc Monotherapy
- Changes in .BETA.-Carotene Levels by Long-Term Administration of Natural .BETA.-Carotene Derived from Dunaliella bardawil in Humans.
- Measurement of Retinoids and .BETA.-Carotene 15, 15'-Dioxygenase Activity in HR-1 Hairless Mouse Skin with UV Exposure
- 4-Oxo Retinoic Acid for Refractory Acute Promyelocytic Leukemia in Children with All-Trans Retinoic Acid Therapy.
- Dietary Reference Intakes for Japanese 2010: Fat-Soluble Vitamins
- α-Tocopherol Status and Expression of α-Tocopherol Transfer Protein in Type 2 Diabetic Goto-Kakizaki Rats
- Effects of angiotensin I converting enzyme inhibitors on the renal excretory function, hemodynamics and renin release in isolated perfused rat kidney.
- Plasma Levels of Retinol, Retinol-binding Protein, all-trans Beta-Carotene and Cryptoxanthin in Low Birth Weight Infants.
- Age-related Changes of .ALPHA.-Tocopherol Transfer Protein Expression in Rat Liver.
- Intravascular Large B-cell Lymphoma with Preceding Syndrome of Inappropriate Secretion of Antidiuretic Hormone
- Dietary Reference Intakes for Japanese 2010: Lifestage
- Effect of a-Tocopherol on Oxidative Hemolysis, as Evaluated by Impedance Measurement.
- THE CLINICAL SIGNIFICANCE OF FREE AND ESTERIFIED VITAMIN A OF BLOOD PLASMA
- Sugar-Specific Inhibitory Effects of Wheat Germ Agglutinin and Phytohemagglutinin-E4 on Histamine Release Induced by Basic Secretagogues from Rat Peritoneal Mast Cells and Their Possible Action Sites.
- Developmental Changes of Tetrahydrobiopterin in Rat and Human Erythrocytes.
- Severe bone marrow failure associated with human parvovirus B19 infection in a case with no underlying disorder
- Distribution of Circulating .BETA.-Carotene in Human Plasma Lipoproteins.
- Induction of Apoptosis by Phosphatidylserine.
- Case treated with triple therapy of lamivudine, interferon-β and prednisolone for acute exacerbation of chronic hepatitis B during pregnancy
- Purification and characterization of phospholipase A2 released from rat platelets.