Effects of Vitamin B12-Deficiency on Testes Tissue in Rats.
スポンサーリンク
概要
- 論文の詳細を見る
The state of vitamin B12-deficiency in rats was evaluated by determination of hepatic vitamin B12-dependent enzyme activities after the animals had fed on a vitamin B12-deficient soybean protein diet for 150 days. The effect of vitamin B12-deficiency on testicular tissue was also studied by morphological observations. Growth of vitamin B12-deficient rats was retarded and marked increase in urinary methylmalonic acid was observed. Vitamin B12 contents in the organs were depressed distinctly by the deficiency, especially in testes, vitamin B12 content decreased to 2.5ng/g. Hepatic methionine synthase and methylmalonyl-CoA mutase ac-tivities showed striking depression to 5% of the control rats and extreme vitamin B12-deficiency was confirmed. Testes weight also showed marked decrease together with their relative weight per 100 g body weight. Mor-phological observations of testes of vitamin B12-deficient rats revealed atrophy of the seminiferous tubules and aplasia of sperms and spermatids. The above results proved that vitamin B12-deficiency affected rat testes, and suggested that the rat could be the animal model for elucidation of themechanism of B12 action on testicular functions.
- 財団法人 学会誌刊行センターの論文
著者
-
Wada Masahiro
Department Of Clinical Dietetics And Human Nutrition Faculty Of Pharmaceutical Sciences Josai Univer
-
Tanaka Nobuo
Department Of Agro-environmental Sciences Graduate School Of Bioresource And Bioenvironmental Scienc
-
Yamada Kazuhiro
Department Of Applied Physics And Physico-informatics Faculty Of Science And Technology Keio University
-
TADOKORO Tadahiro
Department of Agricultural Chemistry, Tokyo University of Agriculture
-
MAEKAWA Akio
Department of Agricultural Chemistry, Tokyo University of Agriculture
-
KAWATA Tetsunori
Faculty of Agriculture, Tokyo University of Agriculiure Okayama University
-
FUJIMOTO Naoko
Faculty of Education, Okayama University
-
TAKADA Tomomi
Faculty of Education, Okayama University
-
MORIMOTO Fusako
Faculty of Education, Okayama University
-
YAMADA Kazuhiro
Department of Agricultural Chemistry, Tokyo University of Agriculture
-
WADA Masahiro
Department of Agricultural Chemistry, Tokyo University of Agriculture
関連論文
- Periodontal Tissue Reaction to Mechanical Stress in Mice
- Correction of Inhomogeneous RF Field Using Multiple SPGR Signals for High-Field Spin-Echo MRI
- Aqueous Extract of Kotahla Himbutu (Salacia reticulata) Stems Promotes Oxygen Comsumption and Supresses Body Fat Accumulation in Mice
- Dietary Fiber Suppresses Elevations of Uric Acid and Allantoin in Serum and Urine Induced by Dietary RNA and Increases Its Excretion to Feces in Rats
- Dietary Curdlan Increases Proliferation of Bifidobacteria in The Cecum of Rats
- Effect of Cobalamin on the Allergic Response in Mice
- Curdlan and Gellan Gum, Bacterial Gel-Forming Polysaccharides, Exhibit Different Effects on Lipid Metabolism, Cecal Fermentation and Fecal Bile Acid Excretion in Rats
- Secretion and Excretion of Immunoglobulin A to Cecum and Feces Differ with Type of Indigestible Saccharides
- Changes in Blood Coagulation, Platelet Aggregation, and Lipid Metabolism in Rats Given Lipids Containing Docosahexaenoic Acid
- Accelerating Effect of Chitosan Intake on Urinary Calcium Excretion by Rats
- Effect of Dietary n-3/n-6 Fatty Acid Ratio on the Total Count, Fatty Acid Composition, and Histamine and Leukotriene Concentrations of Mast Cells in Tunica Mucosa Bronchiorum of Type I Allergic Guinea Pig
- Alteration of the responses of gastric smooth muscle to endothelin in streptozotocin-induced diabetic rats
- Interval immobilization technique for recognition toward a highly hydrophilic cyanobacterium toxin
- On-column concentration of bisphenol A with one-step removal of humic acids in water
- Periodontal tissue reaction to mechanical stress in mice(Poster Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)
- Time-Resolved High-Resolution Electron Microscopy of Surface-Diffusion of Tungsten Atoms on MgO (001) Surfaces
- Cloning, Sequencing, and Heterologous Expression of Rat Methionine Synthase cDNA
- Crystal Structure of H_2-Proteinase from the Venom of Trimeresurus flavoviridis
- Crystallization and Preliminary X-Ray Studies of Isocitrate Dehydrogenase from Thermus thermophilus HB8
- Crystallization and Preliminary X-Ray Study of H_2-Proteinase from the Venom of Trimeresurus flavoviridis
- The Crystal Structures of Mutated 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8 and Their Relationship to the Thermostability of the Enzyme
- Anion- and Cation-Exchange MicroHPLC Utilizing Poly(methacrylates)-coated Monolithic Silica Capillary Columns
- Properties of Monolithic Silica Columns for HPLC
- An Examination of the Gelation of Methacrylate Type Crosslinking Agents for the Preparation of Polymer Monolith with 3D Ordered Network Structures
- Novel Surface-modified Molecularly Imprinted Polymer Focused on the Removal of Interference in Environmental Water Samples
- Improved Detectability with a Polymer-based Trapping Device in Rapid HPLC Analysis for Ultra-low Levels of Bisphenol A (BPA) in Environmental Samples
- Capillary Electromatography on Monolithic Silica Columns
- Selective Surface Modification Technique for Improvement of Chromatographic Separation Selectivity for Sugar Derivatives
- Design for Valid "Surface" Property of Polymer-based Separation Media for Capillary Electrochromatography (CEC) : Correlation between Separation Selectivity, Retentivity and Generation of Electroosmotic Flow
- Molecularly Imprinted Uniform-Sized Polymer-Based Stationary Phase for Naproxen
- Uniformly Sized Polymer Based Stationary Phase Having Multi-Chiral Selectors
- Uniform-size Macroporous Polymer-based Stationary Phase for HPLC Prepared through Molecular Imprinting Technique
- Possible Solution to Discord between Void Volume Recovery of Polypeptide and Separation of Drugs with Restricted-access Type Polymer-based Separation Media for HPLC
- Unexpected Effects of Seed Polymer on the Porous Structures of Poly(methyl methacrylate-ethylene glycol dimethacrylate) Particles
- Warfarin reduces the incidence of osteonecrosis of the femoral head in spontaneously hypertensive rats
- Magnetic Properties of Codeposited Fe/MgO Composite Films
- Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a ^P NMR study
- Simultaneous measurements of lactate and blood flow during hypoxia and recovery from hypoxia in a localized region in the brain of the anesthetized rabbit
- A new mutation, ataxia and male sterility (ams), of autoimmuneprone MRL/lpr mouse is not linked to lpr gene but associated with reduction of spleen size and alteration of lymphocyte subpopulations
- Synthesis of Protoporphyrin IX Derivatives Having Four Amphiphilic and/or Lipophilic Alkyl Chains and Their Dispersing Behavior in Phospholipid Bilayer
- Relationship between T_c and Cu Valence and Bond Lengths of Cu-Cu and Cu-O for Ba_Eu_Cu_3O_ Compounds
- In-vitro assessment of fabric structural composite scaffold applicable to tissue regeneration around implants
- Effects of hand shapeand posture on vascular hunting reaction of hand
- 正常咬合者の顎顔面形態と咬合力の関連
- Glucosamine Regulates Differentiation of a Chondrogenic Cell Line, ATDC5(Molecular and Cell Biology)
- Proportion of Murine Cytotoxic T Cells is Increased by High Molecular-Weight Fucoidan Extracted from Okinawa mozuku (Cladosiphon okamuranus)
- Severe Ascites with Hypothyroidism and Elevated CA125 Concentration : A Case Report
- Electron Energy-Loss Spectroscopy of Carbon Films Prepared by Electron-Cyclotron-Resonance Plasma Sputtering
- Signal transduction and transcriptional regulation during mesenchymal cell differentiation
- The effect of local bFGF administration for growth of mouse mandiblar head(Poster Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)
- Crystallization and Preliminary X-Ray Analysis of Cytochrome c-554 from Nitrosomonas europaea
- LPS-stimulated Apert Syndrome Gingival Keratinocytes Show Markedly Suppressed Inflammatory Cytokine Production
- Is old age a risk factor for dental implants?
- Improvement of Alkaliphily of Bacillus Alkaline Xylanase by Introducing Amino Acid Substitutions Both on Catalytic Cleft and Protein Surface
- Production of Single-Wall Nanotubes by High-Temperature Pulsed Arc Discharge:Mechanisms of their Production
- ADENOCARCINOMA IN SITU ARISING FROM THE ECTOPIC SUBMUCOSAL CARDIAC GLANDS OF SHORT-SEGMENT BARRETT'S EPITHELIUM
- CASE OF A MINUTE SESSILE LESION OF THE SIGMOID COLON WITH MASSIVE CANCER INVOLVEMENT IN THE SUBMUCOSAL LAYER
- RARE GASTRIC CALCIFYING FIBROUS PSEUDOTUMOR REMOVED BY ENDOSCOPIC SUBMUCOSAL DISSECTION
- A Calcium-Dependent Xylan-Binding Domain of Alkaline Xylanase from Alkaliphilic Bacillus sp. Strain 41M-1
- Safety Evaluation of the Aqueous Extract Kothala Himbutu (Salacia reticulata) Stem in the Hepatic Gene Expression Profile of Normal Mice Using DNA Microarrays
- Highly Sensitive Sizing Response Induced by 2-Bromination of Fatty Acids and their Pairing with Anchor Sites Formed on Paper Surfaces
- Electron Microscopy of Composite Films of Titanium and Magnesium Oxide
- High Resolution Electron Microscopy of Composite Films of Iron and Magnesium Oxide
- High Resolution Electron Microscopy of Composite Films of Gold and Magnesium Oxide
- Hydrogen-Storage Properties and Structure Characterization of Melt-Spun and Annealed Mg-Ni-Nd Alloy
- First observation of SiO_2/Si(100) interfaces by spherical aberration-corrected high-resolution transmission electron microscopy
- Infrared Spectroscopy of Metal-MgO Single Crystalline Composite Films
- Electron Microscopic Observation of PbS Islands
- Detection of Strain in InP/InGaP Superlattices by Dark-Field Electron Microscopy and Nano-Diffraction Technique
- HRTEM and EELS Studies of L1_0-Ordered FePt nano-Clusters on MgO Films Prepared Below 673K
- 117 Generation of a Quiet Zone in a Thin Plate Using ABC(O.S.2 Vibration and Noise Reduction Technology III)
- ACTIVE CLUSTER CONTROL OF STRUCTURE-BORNE SOUND RADIATED FROM A PLANAR STRUCTURE USING ACOUSTIC CLUSTER FILTERING
- Position dependence of the visibility of a single gold atom in silicon crystals in HAADF-STEM image simulation
- Effects of Dietary n-3/n-6 and Polyunsaturated Fatty Acid/Saturated Fatty Acid Ratios on Platelet Aggregation and Lipid Metabolism in Rats
- Dietary Fiber Suppresses Elevations of Uric Acid and Allantoin in Serum and Urine Induced by Dietary RNA and Increases Its Excretion to Feces in Rats
- Changes in Platelet Aggregation and Lipid Metabolism in Rats Given Dietary Lipids Containing Different n-3 Polyunsaturated Fatty Acids
- Effect of Indigestible Saccharides on B Lymphocyte Response of Intestinal Mucosa and Cecal Fermentation in Rats
- Ferromagnetic Resonance in Single Crystals of Cobalt-Substituted Nickel Ferrite
- Vibroacoustic Independent Contributors and Active Control of Vibration and Sound in Double Walls: Part II. Cluster Control
- ACTIVE WAVE CONTROL OF A FLEXIBLE BEAM USING DISTRIBUTED PARAMETER SENSORS
- Vibration Control of a Flexible Beam Using ABC Method
- Beam alignment and related problems of spherical aberration corrected high-resolution TEM images
- Observation of Lattice Images for θ' Precipitates in Al-4% Cu Alloys
- Nanometer-Area Electron Diffraction of Interfaces of Semiconductor Superlattices : Techniques, Instrumentations and Measurement
- 118 ACTIVE POWER FLOW CONTROL OF A PLANAR STRUCTURE : GENERATION OF A QUIET ZONE BY USING CLUSTER FEEDBACK CONTROL(O.S.2 Vibration and Noise Reduction Technology III)
- Theoretical basis of image-deconvolution method for structure images of thin crystals
- An auto-tuning method for focusing and astigmatism correction in HAADF-STEM, based on the image contrast transfer function
- 125 ACTIVE CONTROL OF SOUND TRANSMISSION WITH POINT ACTUATORS UTILIZING THE MECHANISM OF ANTI-RESONANCE PHENOMENON(O.S.3 Noise and Sound Control II)
- ACTIVE PROGRESSIVE WAVE CONTROL OF A SIMPLY SUPPORTED PLATE
- Oral administration of N-acetyl Glucosamine alters the mRNA expression profile of hyaluronan-related genes in mouse skin
- Target-Tracking based on Fusion of Unsynchronized Sensor Data from Vision System and Thermal Imaging Sensor
- The molecular structure of bromo(ethyl)((-)-sparteine)magnesium(II), a catalyst for the asymmetric-selective polymerization of racemic methacrylates.
- Studies of Diazosulfides. I. A Kinetic Study of the Reaction of Diaryldiazosulfides with β-Naphthol in Alkaline Ethanol
- The molecular structure of tricarbonyl(triple-layered[2.2]paracyclophane)chromium at -95.DEG.C(monoclinic form) and -160.DEG.C(triclinic form).
- Molecular structure of (2)(2,5)(7,7,8,8-tetracyanoquinodimethano)-(2)(1,4)naphtalenophane.
- Preliminary X-ray studies of thermostable mutants of carboxyl-terminal modified 3-isopropylmalate dehydrogenase, HD711
- Effects of Vitamin B12-Deficiency on Testes Tissue in Rats.
- The crystal and molecular structure of (acetylacetonato)-(diacetylmethyl)(diethylamine)palladium(II).
- The 2.0.ANGS. crystal structure of cyanide metmyoglobin reconstituted with 5,10,15,20-tetrapropylhemin.
- The crystal structure of bis(acetylacetonato)platinum(II) benzene solvate.