Proportion of Murine Cytotoxic T Cells is Increased by High Molecular-Weight Fucoidan Extracted from Okinawa mozuku (Cladosiphon okamuranus)

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概要

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• Male BALB/c mice were administered three fucoidans with different molecular weights prepared from Okinawa mozuku (Cladosiphon okamuranus). The proportion of CD8^+ cells in the spleens of mice fed with high molecular-weight fucoidan significantly increased compared with those in mice fed a control diet. In addition, the CD4^+/CD8^+ ratio tended to decrease and the proportion of CD11b^+ cells to increase. These results suggest that high molecular-weight fucoidan promotes an increase in the proportion of murine cytotoxic T cells.

• 公益社団法人日本薬学会の論文
• 2005-06-01

著者

• WADA Masahiro

  Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Science, Josai Unive

• SHIMIZU Jun

  Department of Nutritional Science, Faculty of Applied Bio-Science, Tokyo University of Agriculture

• 清水 純

  城西大学

• Mano Hiroshi

  Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Sciences, Josai Univ

• Shimizu Jun

  Department Of Clinical Dietetics And Human Nutrition Faculty Of Pharmaceutical Sciences Josai Univer

• Matahira Yoshiharu

  Research And Development Yaizu Suisankagaku Industry Co. Ltd.

• Matahira Yoshiharu

  Research & Developing Division Yaizu Suisankagaku Industry Co. Ltd.

• Wada Masahiro

  Department Of Clinical Dietetics And Human Nutrition Faculty Of Pharmaceutical Sciences Josai Univer

• Mano Hiroshi

  Department Of Clinical Dietetics And Human Nutrition Faculty Of Pharmaceutical Sciences Josai Univer

• Mano Hiroshi

  Department Of Agricultural Chemistry Faculty Of Agriculture Tokyo University Of Agriculture

• Funada Urara

  Department of Clinical Dietetics & Human Nutrition, Faculty of Pharmaceutical Science, Josai Univers

• Kawaguchi Mitsuaki

  Research & Developing Division, Yaizu Suisankagaku Industry Co., Ltd.

• Funada Urara

  Department Of Clinical Dietetics & Human Nutrition Faculty Of Pharmaceutical Science Josai Unive

• Kawaguchi Mitsuaki

  Research & Developing Division Yaizu Suisankagaku Industry Co. Ltd.

• Mano Hiroshi

  Faculty of Pharmaceutical Science, Josai University

• Wada-Funada Urara

  Department of Clinical Dietetics & Human Nutrition, Faculty of Pharmaceutical Science, Josai University

• WADA Masahiro

  Department of Agricultural Chemistry, Tokyo University of Agriculture

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