S-Methylcysteine Sulfoxide (Methiin) の栄養学的価値に関する研究 : (V) Methiin の Methionine 代用性とアミノ酸 imbalance の有無について

概要

論文の詳細を見る
Comparative studies on the effects of S-methylcysteine sulfoxide (SMCS), S-allylcysteine sulfoxide (SACS) and methionine on rats were carried out.Experiment No. 1Young male Wistar rats were separated into five groups and five synthetic diets (amino acids mixture was used as protein source) were given. To group 1, methionine and cystine deficient diet; to group 2, SMCS supplemented to methionine and cystine deficient diet; to group 3, SACS supplemented to methionine and cystine deficient diet; to group 4, cystine supplemented to methionine deficient diet; and to group 5, complete amino acid mixture diet were given.In group 5, good growth was observed while body weight in group 1, 2, 3 and 4 showed progressive loss and after 20∼30 days these animals died.These facts suggested that SMCS, SACS and cystine had no methionine-substitution effect on the growth of methionine-cystine deficient rats.Experiment No. 2Adult male Wistar rats were separated into six groups and six semisynthetic diets were given. Group 1, low protein diet (5% casein); group 2, high protein (15% casein); group 3, low protein plus 2% methionine; group 4, high protein plus 2% methionine; group 5, low protein plus 2% SMCS; group 6, high protein plus 2% SMCS containing diet. After two weeks of these dietary regimens, the animals were sacrificed and various examinations were carried out.Increase of liver triglyceride, abnormal pattern of fatty acids in liver and decrease in serum threonine were prominent in group 3. While in the other groups such abnormalities were not seen.From these findings, it was clarified that even when an excessive amount of SMCS was added to the low protein diet, this amino acid do not produce symptoms of amino acid imbalance as seen in rats fed excessive amount of methionine.
日本衛生学会の論文

S-Methylcysteine Sulfoxide (Methiin) の栄養学的価値に関する研究 : (V) Methiin の Methionine 代用性とアミノ酸 imbalance の有無について

スポンサーリンク

概要

著者

関連論文

スポンサーリンク