FORMATION OF ESTROGENS IN THE FETO-PLACENTAL COMPARTMENTS
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概要
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Labelled dehydroepiandrosterone and androstenedione were injected into the umbilical vein at cesarean section in the mid trimester, and the formation of estrogens in the feto-placental compartments was investigated. Estrone, estradiol-7β and estriol were formed in this system of these precursors. Radioactive estriol found in the fetal liver was higher in concentration than that in the cord blood or placenta. Estriol was formed from dehydroepiandrosterone more efficiently than androstenedione in the feto-placental unit.The conversion rate to estriol in the maternal urine well correlated with the ratio of estriol formed in the cord blood.Estrogen metabolism during pregnancy was also discussed.
- 社団法人 日本内分泌学会の論文
著者
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SATOH Kazuo
Department of Electronic Engineering, Faculty of Engineering, Osaka University
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Yanaihara Takumi
Department Of Obstetrics And Gynecology School Of Medicine Showa University
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Nakayama Tetsuya
Department Of Obstetrics And Gynecology School Of Medicine Showa University
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Fujita Yoshihisa
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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Arai Kiyoshi
Department Of Pediatric Dentistry Nihon University Graduate School Of Dentistry At Matsudo
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NAGATOMI KEIJI
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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TABEI TORU
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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Fujita Yoshihisa
Department Of Anesthesiology & Intensive Care Medicine Kawasaki Medical School
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Arai Kiyoshi
Department Of Obstetrics And Gynecology Teikyo University School Of Medicine
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ARAI KIYOSHI
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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