Metabolic Fate of <SUP>3</SUP>H-Testosterone Administered into the Fetoplacental Compartments
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概要
- 論文の詳細を見る
A tracer amount of 3 H-testosterone was administered into the umbilical vein at full term cesarean section and was allowed to circulate in the feto-placental compartments for 10 min before the baby was delivered. Cord blood and maternal and neonatal urine were analysed for radioactive metabolites. Besides unchanged testosterone, androstenedione, estrone, estradiol-17β and estriol were found in these samples. In urine, radioactive 17-KS was also detected. It was noteworthy that estrogens were detected in the circulating cord blood after such a short time. Among three classical estrogens, the ratio of estriol was the highest of all the samples analysed. This fact suggests that testosterone, if produced at all in the fetal testis, would undergo metabolic changes in the placenta and consequently it is not related to the concentration in the cord blood.
- 社団法人 日本内分泌学会の論文
著者
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KOBAYASHI Takuro
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu Univers
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Arai Kiyoshi
Department Of Pediatric Dentistry Nihon University Graduate School Of Dentistry At Matsudo
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EGUSA MASAKO
Department of Obstetrics and Gynecology, Faculty of Medicine University of Tokyo
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OH RAN
Department of Obstetrics and Gynecology, Faculty of Medicine University of Tokyo
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Kobayashi Takuro
Department Of Dermatology Field Of Sensory Organology Kagoshima University Graduate School Of Medica
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Arai Kiyoshi
Department Of Obstetrics And Gynecology Teikyo University School Of Medicine
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KOBAYASHI TAKURO
Department of Obstetrics and Gynecology, Faculty of Medicine University of Tokyo
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