A Radioimmunoassay of Serum 16α-Hydroxypregnenolone With Specific Antiserum
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概要
- 論文の詳細を見る
A radioimmunoassay for plasma 16α-hydroxypregnenolone has been developed using anti-16α-hydroxypregnenolone antiserum produced in rabbits immunized with 16α-hydroxypregnenolone-3-succinate-bovine serum albumin. Radioimmunoassay data were processed and analysed for its validity using a four parameter logistic curve fitting routine with use of the IBM call system. The assay system was satisfactory a routine use.<BR>The 16α-hydroxypregnenolone concentrations in the umbilical cord blood at term ranged from 223 to 324 ng/m<I>l</I>. Gas liquid chromatographic analysis revealed a similar result, and also the presence of this steroid in the adrenal gland of the human fetus at midtrimester was confirmed. It is speculated that this steroid is secreted from fetal adrenals.
- 社団法人 日本内分泌学会の論文
著者
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Okinaga Shoichi
Department of Obstetrics & Gynecology, Teikyou University, School of Medicine, Ichihara Hospital,
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Arai Kiyoshi
Department Of Pediatric Dentistry Nihon University Graduate School Of Dentistry At Matsudo
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Yamamoto Toshiro
Department Of Microbiology Kyoto Prefectural University Of Medicine
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Shibusawa Haru
Department Of Chemistry Faculty Of Science Ochanomizu University
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Satoh Naoki
Department Of Cardiology Tokyo Women's Medical University
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SANO YUMIKO
Department of obstetrics and Gynecology, Teikyo University School of Medicine
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KAMBEGAWA AKIRA
Research Laboratory, Teikoku Hormone Mfg. Co., Ltd.
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OHIKAWA TOMI
Department of obstetrics and Gynecology, Teikyo University School of Medicine
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Arai Kiyoshi
Department Of Obstetrics And Gynecology Teikyo University School Of Medicine
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SATOH NAOKI
Department of obstetrics and Gynecology, Teikyo University School of Medicine
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SANO YUMIKO
Department of Obstetrics and Gymecology, Teikyo University School of Medicine
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YAMAMOTO TOSHIRO
Department of obstetrics and Gynecology, Teikyo University School of Medicine
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SHIBUSAWA HARU
Department of obstetrics and Gynecology, Teikyo University School of Medicine
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