Stimulation of Pitutitary Glucose-6-Phosphate Dehydrogenase Activity in the Rat Associated with Increased TSH Secretion

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概要

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• Pituitary G-6-PDH activity was increased when pituitary weight is augmented by the use of a low iodine diet or treatment with methiocil for a few weeks. In contrast, pituitary enzyme activity was decreased by T<SUB>4</SUB> treatment.<BR>The increased enzyme activity may be due to the increased weight of pituitary as a result of prolonged elevation of TSH secretion. However, the augmentation of pituitary weight was less pronounced following treatment with methiocil or low iodine in comparison with the increase in thyroid weight. Therefore, the augmentation of total enzyme activity in the pituitary was less than that in the thyroid. This experiment showed that pituitary G-6-PDH activity is increased in the pituitary gland when a continuous increase in TSH secretion occurs.

• 社団法人 日本内分泌学会の論文

著者

• YOSHIMURA Manabu

  Second Department of Internal Medicine. Kyoto Prefectural University of Medicine

• TAKAHASHI HAKUO

  Second Department of Medicine, Kyoto Prefectural University of Medicine

• HACHIYA TAKASHI

  Second Department of Surgery, Hamamatsu University School of Medicine

• Ochi Y

  Research Institute For Production Development

• Kaimasu Isao

  Second Department Of Internal Medicine Kyoto Prefectural University Of Medicine

• MIYAZAKI TADAYOSHI

  Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto

• OCHI YUKIO

  Second Department of Internal Medicine Shiga University of Medical Science

• MAJIMA TAKAYA

  Second Department of Internal Medicine, Shiga Medical University

• YOSHIMURA MANABU

  Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto

• TAKAHASHI Hakuo

  Second Department of Internal Medicine, Kyoto Prefectural University of Medicine

• HACHIYA Takashi

  Second Department of Internal Medicine, Kyoto Prefectural University of Medicine

• HACHIYA TAKASHI

  Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto

• MIYAZAKI TADAYOSHI

  Second Department of Internal Medicine, Kyoto Prefectural University of Medicine

• MAJIMA TAKAYA

  Second Department of Internal Medicine, Kyoto Prefectural University of Medicine

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