Urinary Excretion of LATS in a Patient with Gravesdisease Complicated by Nephrotic Syndrome
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概要
- 論文の詳細を見る
A case report of a female patient with Graves disease complicated by nephrotic syndrome with high LATS activity in urinary gamma-globulin is presented. When in the hyperthyroid state with high LATS activity in the serum, she was treated with antithyroid drugs, excess iodine, and finally radioisotopes. Mild hypothyroidism occurred transiently without any significant change in serum LATS activity. Nephrotic syndrome suddenly appeared. Urinary IgG was purified by salting out with ammonium sulfate, DEAE and protein A-Sepharose, and LATS activity in the purified urinary IgG fraction was demonstrated. The specific activity of LATS activity in urinary IgG protein was slightly lower than that of the serum.<BR>This case is the first demonstration of LATS activity in urine from a patient with hyperthyroidism and nephrotic syndrome.
- 社団法人 日本内分泌学会の論文
著者
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YOSHIMURA Manabu
Second Department of Internal Medicine. Kyoto Prefectural University of Medicine
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KAJITA YOSHIHIRO
Nantan General Hospital
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HACHIYA TAKASHI
Second Department of Surgery, Hamamatsu University School of Medicine
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KAJITA YOSHIHIRO
Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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MIYAZAKI TADAYOSHI
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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OCHI YUKIO
Second Department of Internal Medicine Shiga University of Medical Science
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MIYOSHI YOSHIKO
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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IJIICHI HAMAO
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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YOSHIMURA MANABU
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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KAJITA YOSHIHIRO
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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HACHIYA TAKASHI
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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