Serum T<SUB>3</SUB> Level in the Patients with Hyperthyroidism After Therapy
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概要
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Serum T<SUB>3</SUB> level in various thyroid diseases was determined in unextracted serum with the Dainabot kit for T<SUB>3</SUB> RIA. The serum T<SUB>3</SUB> level in 33 normal subjects was 0.8-1.6ng/ml. It was 5.7±3.5ng/ml (mean± S.D.) in 36 hyperthyroid patients, and undetectable to 0.8 ng/ml in 21 hypothyroid patients.<BR>Generally the serum T<SUB>4</SUB> and serum T<SUB>3</SUB> decreased in parallel after radioiodine therapy for hyperthyroidism. However, in some cases the serum T<SUB>3</SUB> level remained high in spite of normalized serum T<SUB>4</SUB> after radioiodine therapy. This state indicated "T<SUB>3</SUB>-toxicosis", and hyperthyroidism was apt to recur. When thyroid function was observed for 2 years following radioiodine treatment, the ratio of serum T<SUB>3</SUB> (T<SUB>3</SUB> level before treatment/T<SUB>3</SUB> level after treatment) decreased more significantly as compared with the ratio of serum T<SUB>4</SUB> in euthyroid cases. Serum T<SUB>3</SUB> provides a more sensitive index of thyroid function than serum T<SUB>4</SUB> in euthyroid states after radioiodine or anti-thyroid drug therapy.<BR>The present data indicate that the serum T<SUB>3</SUB> level and the T<SUB>4</SUB>/T<SUB>3</SUB> ratio are valuable aids in the estimation of prognosis of hyperthyroid patients after various treatments.
- 社団法人 日本内分泌学会の論文
著者
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HACHIYA TAKASHI
Second Department of Surgery, Hamamatsu University School of Medicine
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MIYAZAKI TADAYOSHI
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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OCHI YUKIO
Second Department of Internal Medicine Shiga University of Medical Science
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YOSHIMURA MANABU
Second Department of Internal Medicine Kyoto Prefectural University of Medicine Kyoto
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