Re-evaluation of Exercise as a Screening Test for Ruling out Human Growth Hormone Deficiency

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概要

• 論文の詳細を見る

• Human growth hormone (HGH) response to exercise was studied in 27 normal children and 152 children with a chief complaint of short stature and in 9 patients with HGH deficency. Of the 152 children 107 could be ruled out of HGH deficiency since HGH level increased to more than 5ng/m<I>l</I> during exercise, and of the remaining children of non-responders to exercise, 22 were ruled out of HGH deficiency since bone age to chronological age ratio was more than 0.9 and/or height increment for the past 3 years was more than 15cm. Seventeen patients were hospitalized for further examinations, which resulted in finding normal HGH secretion in response to insulin-induced hypoglycemia, arginine infusion and/or propranolol-glucagon test 12 children and also in finding no HGH deficiency in children higher than-2.0 S. D., but 5 HGH-deficient children in those lower than-2.0 S.D. Exercise can be used as a screening test for ruling out HGH deficiency when HGH secretion in response to exercise is evaluated by height, bone age and height increment of the patients.

• 社団法人 日本内分泌学会の論文

著者

• Onishi Toshio

  Department Of Fisheries Faculty Of Agriculture Tohoku University

• Kumahara Yuichi

  Department Of Medicine And Ceriatrics Oska University Medical School

• Okada Yoshiaki

  Department Of Bacterial And Blood Products National Institute Of Infectious Diseases

• Okada Y

  Hanwa Senboku Hospital Osaka

• TANAKA KIYOJI

  Department of Medicine and Geriatrics, Osaka University

• TSUJI MITSUKO

  Department of Medicine and Geriatrics, Osaka University

• Morimoto Shigeto

  Department Of Epidemiological And Clinical Research Information Management Kyoto University Graduate

• WATANABE KAZUO

  Yodogawa Christian Hospial

• TAKEUCHI TORU

  Yodogawa Christian Hospial

• ONISHI TOSHIO

  Department of Medicine and Ceriatrics, Osaka University School of Medicine

• MORIMOTO SHIGETO

  Department of Medicine and Ceriatrics, Osaka University School of Medicine

• TANAKA KIYOJI

  Department of Medicine and Ceriatrics, Osaka University School of Medicine

• OKADA YOSHIAKI

  Department of Medicine and Ceriatrics, Osaka University School of Medicine

• TSUJI MITSUKO

  Department of Medicine and Ceriatrics, Osaka University School of Medicine

• TAKEUCHI TORU

  Yodogawa Christian Hospital

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