A Screening Test to Detect HGH-Antibodies in Pituitary Dwarfs Treated with HGH Preparation by the Radioimmunoassay with Double Antibody Technique
スポンサーリンク
概要
- 論文の詳細を見る
Sixty-four blood samples, obtained from 25 pituitary dwarfs treated with KABIHGH preparation, were checked for serum HGH concentration by a double antibody radioimmunoassay and for antibodies against HGH by the method of propylethyleneglycol separation. Antibodies to HGH were detected in the samples whose HGH concentration was falsely estimated to be more than 5ng/m<I>l</I>, but not in those whose HGH concentration was 5ng/m<I>l</I> or less. The measurement of HGH concentration by a double antibody technique in the serum obtained from pituitary dwarfs 3-4 days after the last injection can be used to screen the presence of antibodies to HGH preparation used.
- 社団法人 日本内分泌学会の論文
著者
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Kumahara Yuichi
Department Of Medicine And Ceriatrics Oska University Medical School
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Okada Yoshiaki
Department Of Bacterial And Blood Products National Institute Of Infectious Diseases
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TAKAHASHI TATSUO
Yodogawa Christian Hospital
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