EVALUATION OF HYPOTENSIVE MECHANISMS OF CAPTOPRIL IN ADDITION TO ITS INHIBITION OF THE CONVERTING ENZYME IN SPONTANEOUSLY HYPERTENSIVE RATS
スポンサーリンク
概要
- 論文の詳細を見る
In spontaneously hypertensive rats (SHR), the hypotensive effect of captopril (30 mg/kg/day per os for 4 days), which inhibits the converting enzyme when given orally, was significantly potentiated rather than suppressed by aprotinin (100,000 KlU/day s.c. for 7 days), but was not affected by indomethacin. These findings suggest that neither the kallikrein-kinin system nor the prostaglandin system is involved in any of the hypotensive actions of captopril in SHR other than the inhibition of the converting enzyme.
- 社団法人日本循環器学会の論文
- 1982-11-20
著者
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OGIHARA Toshio
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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MIKAMI Hiroshi
Department of Health Promotion Science, Osaka University Graduate School of Medicine
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Ogihara Toshio
Department Of Geriatic Medicine
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Kumahara Yuichi
Department of Medicine and Geriatrics, Osaka University Medical School
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Ohde Hironori
Department Of Medicine And Geriatrics Osaka University Medical School
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Mikami Hiroshi
Department Of Community Health Nursing Osaka University Graduate School Of Medicine
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KUMAHARA YUICHI
The Department of Medicine and Geriatrics, Osaka University Medical School
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Mikami Hiroshi
Department Of Geriatric Medicine Osaka University Medical School
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NAKA TORU
Department of Medicine and Geriatrics, Osaka University Medical School
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Ogihara Toshio
Department Of Medicine And Gerictrics Osaka University Medical School
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Naka Toru
Department Of Medicine And Geriatrics Osaka University Medical School
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Kumahara Yuichi
The Department Of Medicine And Geriatrics Osaka University Medical School
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Kumahara Yuichi
Department Of Medicine And Ceriatrics Oska University Medical School
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Kumahara Yuichi
Department Of Medicine And Geriatrics Osaka University Medical School:sakurabashi Watanabe Hospital
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Kumahara Y
Department Of Medicine And Geriatrics Osaka University Medical School:sakurabashi Watanabe Hospital
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Kumahara Yuichi
The Central Laboratory For Clinical Investigation Osaka Univ. Hosp. Osaka And The Center For Adult D
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