State-dependent effects of .BETA.-endorphin on core temperature in stressed and non-stressed rats.
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概要
- 論文の詳細を見る
β-Endorphin, γ-endorphin, δ-endorphin and morphine injected i.c.v. caused hyperthermia in non stressed rats; however, the same dose of β-endorphin and morphine caused hypothermia in stressed animals. These effects of β-endorphin were antagonized by naloxone. The results suggest that effects of β-endorphin are different depending on the animal's state and that these effects are mediated via opioid receptors.
- 公益社団法人 日本薬理学会の論文
著者
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Tsuda Akira
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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Ida Yoshishige
Department Of Pharmacology Kurume University School Of Medicine
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USHIJIMA Itsuko
Department of Neuropsychiatry, Yamaguchi University School of Medicine
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Nagasaki Nobuyuki
Department Of Pharmacology Kurume University School Of Medicine
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Tanaka Masatoshi
Department Of Comprehensive Management Matsumoto University
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TSUJIMARU Shusaku
Department of Pharmacology, Kurume University School of Medicine
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