Effects of aniracetam, a nootropic drug, in senile dementia. A preliminary report.:A Preliminary Report
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概要
- 論文の詳細を見る
Three female patients with dementia were given aniracetam 500 mg, 1000 mg, and placebo for 4-week periods in a double-blind, cross-over study. EEGs and psychometric tests were performed before and during the treatment. From the power percentage of EEGs, aniracetam 500 mg produced an increase of α and fast wave activities but a decrease of slow wave activity. With aniracetam 1000 mg, neither an increase of α activity nor a decrease of slow wave activity were observed. In the psychometric tests, only the patient with a mild dementia responded favorably, according to performance on the tests. However, the scores with aniracetam 500 mg were higher than those with aniracetam 1000 mg. These results indicate that aniracetam may only be effective when dementia is mild and when the dose is carefully titrated.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Yamada Michio
Department of Cardiovascular Medicine, Medical Bioregulation, Yamaguchi University School of Medicin
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Mizuki Yasushi
Department Of Neuropsychiatry Yamaguchi University School Of Medicine
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INANAGA Kazutoyo
Department of Nernropsychiatry and Institute of Brain Diseases, Kurume University School of Medicine
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Tanaka Masatoshi
Department Of Comprehensive Management Matsumoto University
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Kato Ichiro
Department Of Applied Physics University Of Tokyo: Fujitsu Laboratories Ltd.
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TAKADA YOSHIKO
Departments of Neuropsychiatry, Kurume University School of Medicine
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TSUJIMARU SHUSAKU
Departments of Neuropsychiatry, Kurume University School of Medicine
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TSUJIMARU Shusaku
Department of Pharmacology, Kurume University School of Medicine
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KATO ICHIRO
Departments of Neuropsychiatry, Kurume University School of Medicine
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