Effects of neuroleptics on dopamine release from striatal slices.
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概要
- 論文の詳細を見る
The effects of neuroleptics on dopamine release from rat striatal slices was investigated with a superfusion system. Haloperidol (10<SUP>-5</SUP>M), chlorpromazine (10<SUP>-4</SUP>M) and sulpiride (10<SUP>-3</SUP>M) induced a significant increase in dopamine efflux from rat striatal slices. The onset of the enhancement of dopamine efflux was slower with superf usion of haloperidol than with methamphetamine. This data suggests that the mechanism of enhancement of dopamine efflux by haloperidol may be different from the mechanism of methamphetamine.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Yamada Shigeto
Institute Of Brain Diseases Kurume University School Of Medicine
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INANAGA Kazutoyo
Department of Nernropsychiatry and Institute of Brain Diseases, Kurume University School of Medicine
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Yokoo Hideyasu
Institute Of Brain Diseases Kurume University School Of Medicine
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TSUTSUMI TETSUYUKI
Institute of Brain Diseases Kurume University School of Medicine
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NISHI SYOGORO
Institute of Brain Diseases Kurume University School of Medicine
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KOJIMA HIDEKI
Institute of Brain Diseases
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ANRAKU SHIGEMI
Institute of Brain Diseases
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TAKAMUKI KAZUYOSHI
Department of Neuropsychiatry, Kurume University School of Medicine
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