Effects of d-amphetamine on activity-stress ulcers in rats.
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概要
- 論文の詳細を見る
Rats were given d-amphetamine alone, placebo or d-amphetamine and food. They were then placed in the activity-stress ulcer paradigm, involving continuous access to a running wheel while being fed for only 1 hr. per day. Animals given d-amphetamine only ran more and died significantly sooner than animals in any other group. These rats also displayed significantly more gastric glandular ulcers than rats in any other group. Rats given d-amphetamine and food exhibited increased running but did not die sooner and displayed ulceration comparable to placebo rats. It appears that neither restricted feeding nor increased running wheel activity is a sufficient cause of activity-stress ulcers; rather, the combined interaction. of both of these variables appears to produce the observed gastric damage.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Tsuda Akira
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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VINCENT GEORGE
Pavlovian Research Laboratory, Veterans Administration Medical Center
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GLAVIN GARY
Department of Psychology, University of Winnipeg
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PARÉ WILLIAM
Pavlovian Research Laboratory, Veterans Administration Medical Center
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