Levels of neurokinin A, neurokinin B and substance P in rabbit iris sphincter muscle.
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概要
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We investigated the contents of neurokinin A, neurokinin B and substance P in the rabbit iris sphincter muscle, combining HPLC and radioimmunoassay, as our previous reports indicated that a slow component of neurogenic contractions of this muscle is most probably mediated by such tachykinins. The concentrations of these tachykinins were 44.3±8.7 fmol/mg protein, 35.3±10.2 fmol/mg protein and 186.8±29.8 fmol/mg protein (N=4), respectively. These results demonstrated that neurokinin A, neurokinin B and substance P are all present in the rabbit iris sphincter muscle.
- 公益社団法人 日本薬理学会の論文
著者
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Kanazawa Ichiro
Department Of Degenerative Neurological Diseases National Institute Of Neuroscience National Center
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Fujiwara Motohatsu
Department Of Pharmacology Faculty Of Medicine Kyoto University
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TANIGUCHI Takashi
Department of Computational Science and Engineering, Nagoya University
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KANAZAWA Ichiro
Department of Neurology, Institute of Clinical Medicine, University of Tsukuba
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MASUO Yoshinori
Department of Neurology, Institute of Clinical Medicine, University of Tsukuba
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Taniguchi Takashi
Department of Biology, Kyoto Pharmaceutical University
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