Inhibitive Effects of Alkyl Gallates on Hyaluronidase and Collagenase

元データ 社団法人 日本農芸化学会

概要

A series of the gallate esters of n-alkanols (C1–C12) was examined to determine their inhibitory activities against hyaluronidase and collagenase. Hexyl, heptyl, octyl, nonyl, and decyl gallates inhibited both hyaluronidase and collagenase, and the most potent inhibitor was octyl gallate against both enzymes. Octyl 3,5-dihydroxybenzoate showed inhibitory effects on hyaluronidase, whereas collagenase was inhibited by octyl 3,4-dihydroxybenzoate.

著者

FUJITA Tomoyuki Department of Physics, Kyoto University
INUI Hiroshi Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
NAKANO Yoshihisa Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
YAMAJI Ryoichi Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
HARADA Naoki Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science
Barla Florin Graduate School Of Life And Environmental Sciences Of Osaka Prefecture University
Barla Florin Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
Higashijima Hayato Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
Funai Shingo Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak
SUGIMOTO Keiichiro Department of Applied Biological Chemistry, Graduate School of Life and Environmental Sciences, Osak

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