In Vitro Augmentation of Natural Killer Activity and Interferon-γ Production in Murine Spleen Cells with Agaricus blazei Fruiting Body Fractions
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概要
- 論文の詳細を見る
Aqueous extracts of the Agaricus blazei fruiting body prepared at different temperatures were fractionated by ethanol precipitation with various ethanol concentrations. The original aqueous extracts of A. blazei failed to stimulate natural killer (NK) cell activity in murine spleen cells in vitro, but the strongest effect was observed in a 30% ethanol-soluble-50% ethanol-insoluble fraction prepared from the extract at 40 °C (fraction A-50). Fraction A-50 also showed the strongest augmenting effect on interferon (IFN)-γ production. This augmentation of NK activity and IFN-γ production by fraction A-50 was completely abrogated by a heat treatment.
- 社団法人 日本農芸化学会の論文
- 2005-12-23
著者
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Zhong Ming
Bizen Chemical Co. Ltd.
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YAMAMOTO Itaru
Department of Radiology, Kanazawa Medical University
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Yamamoto Itaru
Department Of Immunochemistry Faculty Of Pharmaceutical Sciences Okayama University
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TAI Akihiro
Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University
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Yamamoto Itaru
Department Of Immunochemistry Faculty Of Pharmaceutical Science Okayama University
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Tai Akihiro
Department Of Immunochemistry Division Of Pharmaceutical Sciences Okayama University Graduate School
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