Augmentation of Antigen-Specific Antibody Production and IL-10 Generation with a Fraction from Rooibos (Aspalathus linearis) Tea
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概要
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Rooibos tea was extracted with boiling water. The aqueous extract was chromatographed in a Diaion HP20 column eluted stepwise with water, 25%, 50% and 75% (v/v) aqueous methanol, and 100% methanol. The water eluate (fraction A) showed an augmenting effect on anti-ovalbumin (anti-OVA) immunoglobulin M (IgM) production in OVA-stimulated murine splenocytes in vitro. Fraction A also showed a strong augmenting effect on interleukin-10 generation in murine splenocytes. Furthermore, continuous ingestion of fraction A was found to increase the anti-OVA IgM level in the sera of OVA-immunized mice.
- 社団法人 日本農芸化学会の論文
著者
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YAMAMOTO Itaru
Department of Radiology, Kanazawa Medical University
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TAI Akihiro
Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University
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ICHIYAMA Kenji
Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University
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