釣藤鈎の研究(第二報) : 中国産釣藤鈎の品質に関する研究

概要

論文の詳細を見る
HPLC profiles of the principal, indole and oxindole alkaloids of a Chinese crude drug "Gou-teng" ("Cho-to-ko" in Japanese) in the Japanese markets showed that the crude drug consisted of three types (S-, R- and SR-Type). The original plant of the samples of R-Type was identified as U. rhynchophylla, and that of S- and SR-Types as U. sinensis by comparison with authentic spacimens. A simple correlation analysis of the alkaloids in the SR-Type samples showed that the geissoschizine methylether content had no correlation with the hirsuteine and hirsutine contents, but that it had negative-correlations with the four oxindole contents. In the SR-Type samples, the samples containing more oxindoles tended to have smaller the geissoscizine methylether content. Of the samples of the three types, only the R-Type samples significantly prolonged the thiopental-induced hypnotics.
日本生薬学会の論文
1998-08-20