Physicochemical Studies on Decoctions of Kampo Prescriptions. III. Effect of the Volume Ratio of the Crude Drug vs. Extractant on the Transfer Ratio of Crude Drug Components into a Model Decoction

元データ 1994-10-15 社団法人日本薬学会

概要

Using a model decoction of Schisandrae Fructus, the effect of the volume ratio of the crude drug vs. extractant was studied. On changing the alteration ratio of the volume ratio according to a two-fold geometric series, the transfer ratios of each lignan into model decoctions generally decreased with increasing alteration ratio. However, the transfer ratios of the high hydrophobic lignans increased partially with the high alteration ratios. As a result, a comprehensive equation involving to the transfer ratios of all the low molecular weight organic components of Schisandrae Fructus in the model decoctions was derived from the analyses of the variant alteration ratios. This equation might be applicable to other crude drug components in kampo decoctions.

著者

田口 平八郎 Tsumura Central Research Laboratories Tsumura & Co.
中島 薫 ツムラ中央研究所
岡田 稔 ツムラ研究本部
丸野 政雄 株式会社 ツムラ ツムラ中央研究所
林 紘司 Tsumura Central Research Laboratories Tsumura & Co.
田口 平八郎 津村研究所
中島 薫 Tsumura Laboratory
丸野 政雄 (株)ツムラ中央研究所
中島 薫 Tsumura Central Research Laboratories Tsumura & Co.
堀内 智子 Tsumura Central Research Laboratories, Tsumura & Co.,
岡田 稔 Tsumura Central Research Laboratories, Tsumura & Co.,
丸野 政雄 Tsumura Central Research Laboratories, Tsumura & Co.,
丸野 政雄 Tsumura Central Research Laboratories Tsumura & Co.
岡田 稔 三共株式会社中央研究所
堀内 智子 Tsumura Central Research Laboratories Tsumura & Co.
岡田 稔 (株)ツムラ中央研究所
林 紘司 (株)ツムラ中央研究所
丸野 政雄 Tsumura Central Research Laboratories

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