Preparation of Optically Active α-Hydroxy Acid Derivatives by Microbial Hydrolysis of Cyanohydrins and Its Application to the Synthesis of (R)-4-Dodecanolide(Organic Chemistry)
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概要
- 論文の詳細を見る
Both enantiomers of aliphatic and aromatic cyanohydrins were hydrolyzed with the aid of Rhodococcus butanica ATCC 21197 to afford optically active α-hydroxy acids. The usefulness of this reaction is demonstrated by the synthesis of optically pure (R)-4-dodecanolide, a defensive secretion of rove beetles, starting from (R)-2-hydroxydecanenitrile.
- 社団法人日本農芸化学会の論文
- 1991-07-23
著者
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Ohta Hiromichi
Department Of Chemistry Faculty Of Science And Technology Keio University
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SUGAI Takeshi
Department of Chemistry, Faculty of Science and Technology, Keio University
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Ohta Hiromichi
Department Of' Chemistry Keio University
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KAKEYA Hideaki
Department of Chemistry, Keio University
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SAKAI Naoko
Department of Chemistry, Keio University
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Ohta H
Keio Univ. Yokohama Jpn
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Ohta Hiromichi
Department Of Applied Chemistry School Of Engineering Nagoya University
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Kakeya H
Antibiotics Laboratory Advanced Science Institute Riken
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Sakai Naoko
Department Of Chemistry Keio University
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Sugai T
Keio Univ. Yokohama Jpn
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Kakeya Hideaki
Department Of' Chemistry Keio University
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Kakeya H
Riken Saitama Jpn
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Kakeya Hideaki
Antibiotics Laboratory Advanced Science Institute Riken
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Sugai Takeshi
Department Of Agricultural Chemistry The University Of Tokyo
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