Synthesis of (S)-Ibuprofen via Enantioselective Degradation of Racemic Ibuprofen with an Isolated Yeast, Trichosporon cutaneum KPY 30802, in an Interface Bioreactor
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概要
- 論文の詳細を見る
An interface bioreactor was used for the enantioselective degradation of (RS)-ibuprofen (IBU). An isolated yeast, Trichosporon cutaneum KPY 30802, preferentially degraded (R)-IBU to accumulate (S)-isomer. The addition of hydroquinone (10 mM) into a hydrophilic carrier was effective for the elevation of enantiomeric excess and the repression of excess degradation of (S)-IBU (E value, 9.3).
- 社団法人日本生物工学会の論文
- 2001-03-25
著者
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Oda Shinobu
Technical Research Laboratory Kansai Paint Co. Ltd.
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Oda Shinobu
Technical Research Laboratory Kansai Paint Co.ltd.
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Ohta Hiromichi
Department Of Chemistry Faculty Of Science And Technology Keio University
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Ohta Hiromichi
Department Of Applied Chemistry School Of Engineering Nagoya University
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Tanaka J
Technical Research Laboratory Kansai Paint Co.ltd.
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TANAKA JUN-ICHI
Technical Research Laboratory, Kansai Paint Co.Ltd.
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