Convulsions in Hemodialysis (HD) Patients with Elevated Polymorphonuclear Leukocyte Elastase (PMNE) Levels
スポンサーリンク
概要
- 論文の詳細を見る
Eight hemodialysis (HD) patients with convulsions of unknown cause were monitored for serum levels of uremic toxins such as methylguanidine (MG), and polymorphonuclear leukocyte elastase (PMNE). Twenty HD patients without convulsions served as controls. In the convulsion group, MG and PMNE were high. In 2 patients, convulsions subsided after daily hemodiafiltration (HDF). Although PMNE was thought to be a mediator of injury in the present series, no significant correlation was found between PMNE and either neutrophil numbers or endotoxin levels. PMNE may indicate the over production of cytokines not associated with serious infection or septicemia. In patients with renal failure and complications of unknown cause, intensified dialysis therapy such as frequent HDF may be useful when combined with treatment of the underlying disease producing the toxins. PMNE measurement is useful in assessing the uremia caused by high cytokine levels and, together with methylguanidin (MG) serum levels, can indicate the severity of the convulsion.
- 東海大学の論文
著者
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Sakai H
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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NOMOTO Yasuo
Division of Nephrology and Metabolism, Department of Internal Medicine Tokai University School of Me
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SAKAI Hideto
Division of Nephrology and Metabolism, Department of Internal Medicine Tokai University School of Me
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Nomoto Yasuo
Departments Of Nephrology And Metabolism; School Of Medicine Tokai University
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Sakai H
Division Of Nephrology And Metabolism Department Of Internal Medicine
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Sakai Hideto
東海大学 医学部腎・内分泌・代謝内科
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Shinbo Takao
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Suga Takao
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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NISHIMURA Tamiko
Division of Nephrology, Department of Internal Medicine, Tokai university Oiso Hospital
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SUGA Takao
Division of Nephrology, Department of Internal Medicine, Tokai university Oiso Hospital
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TAKEMURA Fumio
Division of Nephrology, Department of Internal Medicine, Tokai university Oiso Hospital
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Sakai Hideto
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Nomoto Yasuo
Division Of Nephrology Department Of Internal Medicine School Of Medicine Tokai University
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Sakai Takako
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Sakai Hideto
Department Of Nephrology Tokai University
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Sakai Hideto
Division Of Nephrology Department Of Internal Medicine School Of Medicine Tokai University
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Sato H
Division Of Nephrology And Metabolism Department Of Internal Medicine
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Takemura Fumio
Division Of Nephrology Department Of Internal Medicine Tokai University Oiso Hospital
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Takemura F
Mechanical Engineering Laboratory
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Nishimura Toshihiko
Division Of Nephrology Department Of Internal Medicine Tokai University Oiso Hospital
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Suga Takao
Division Of Nephrology Department Of Internal Medicine Tokai University Oiso Hospital
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Sato Haruhiro
Division Of Nephrology And Metabolism Department Of Internal Medicine
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Sakai Hideto
Department Of Health Care Policy And Management Graduate School Of Comprehensive Sciences University Of Tsukuba
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Sakai Hideto
Division of Nephro-Urology
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